Ethnic inequalities in positive SARS-CoV-2 tests, infection prognosis, COVID-19 hospitalisations and deaths: analysis of 2 years of a record linked national cohort study in Scotland.
Ethnic inequalities in positive SARS-CoV-2 tests, infection prognosis, COVID-19 hospitalisations and deaths: analysis of 2 years of a record linked national cohort study in Scotland.
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DOI：
10.1136/jech-2023-220501
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发表时间：
2023-10
影响因子：
6.3
通讯作者：
Katikireddi, Srinivasa Vittal
中科院分区：
文献类型：
--
作者：
Amele, Sarah;Kibuchi, Eliud;McCabe, Ronan;Pearce, Anna;Henery, Paul;Hainey, Kirsten;Fagbamigbe, Adeniyi Francis;Kurdi, Amanj;McCowan, Colin;Simpson, Colin R.;Dibben, Chris;Buchanan, Duncan;Demou, Evangelia;Almaghrabi, Fatima;Anghelescu, Gina;Taylor, Harry;Tibble, Holly;Rudan, Igor;Nazroo, James;Becares, Laia;Daines, Luke;Irizar, Patricia;Jayacodi, Sandra;Pattaro, Serena;Sheikh, Aziz;Katikireddi, Srinivasa Vittal
这项研究旨在估计苏格兰随着时间的推移，SARS-CoV-2阳性检测、COVID-19住院和死亡风险方面的种族不平等。我们进行了一项基于人群的队列研究，将2011年苏格兰人口普查与健康记录联系起来。我们纳入了截至2020年3月1日居住在苏格兰的所有16岁个人。研究期间为2020年3月1日至2022年4月17日。自我报告的族裔群体来自人口普查，Cox比例风险模型估计了SARS-CoV-2检测阳性、住院和死亡的hr，并根据年龄、性别和健康委员会进行了调整。我们还对COVID-19的四波分别进行了分析，以评估风险随时间的变化。在分析的4358339名个体中，1093234例SARS-CoV-2检测呈阳性，37437例住院治疗，14158例死亡。与苏格兰白人组相比，少数民族群体中白人吉普赛人/旅行者（HR 2.21, 95% CI(1.61至3.06)）和巴基斯坦人（2.09至2.29）组的COVID-19住院或死亡风险往往更高。与苏格兰白人相比，确诊为SARS-CoV-2阳性的吉普赛人/旅行者（2.55(1.81-3.58)）、巴基斯坦人（1.75(1.59-1.73)）和非洲人（1.61(1.28-2.03)）的COVID-19住院或死亡风险尤其高。然而，住院后与covid -19相关的死亡风险没有差异。前三波与第四波相比，少数民族群体的COVID-19结局风险更高。在苏格兰，大多数少数民族群体患COVID-19不良后果的风险增加，尤其是白人吉普赛人/旅行者和巴基斯坦群体。在社区感染后，种族不平等仍然存在，但在住院后就没有了，这表明医院治疗的差异并没有在很大程度上导致种族不平等。
This study aims to estimate ethnic inequalities in risk for positive SARS-CoV-2 tests, COVID-19 hospitalisations and deaths over time in Scotland. We conducted a population-based cohort study where the 2011 Scottish Census was linked to health records. We included all individuals16 years living in Scotland on 1 March 2020. The study period was from 1 March 2020 to 17 April 2022. Self-reported ethnic group was taken from the census and Cox proportional hazard models estimated HRs for positive SARS-CoV-2 tests, hospitalisations and deaths, adjusted for age, sex and health board. We also conducted separate analyses for each of the four waves of COVID-19 to assess changes in risk over time. Of the 4 358 339 individuals analysed, 1 093 234 positive SARS-CoV-2 tests, 37 437 hospitalisations and 14 158 deaths occurred. The risk of COVID-19 hospitalisation or death among ethnic minority groups was often higher for White Gypsy/Traveller (HR 2.21, 95% CI (1.61 to 3.06)) and Pakistani 2.09 (1.90 to 2.29) groups compared with the white Scottish group. The risk of COVID-19 hospitalisation or death following confirmed positive SARS-CoV-2 test was particularly higher for White Gypsy/Traveller 2.55 (1.81–3.58), Pakistani 1.75 (1.59–1.73) and African 1.61 (1.28–2.03) individuals relative to white Scottish individuals. However, the risk of COVID-19-related death following hospitalisation did not differ. The risk of COVID-19 outcomes for ethnic minority groups was higher in the first three waves compared with the fourth wave. Most ethnic minority groups were at increased risk of adverse COVID-19 outcomes in Scotland, especially White Gypsy/Traveller and Pakistani groups. Ethnic inequalities persisted following community infection but not following hospitalisation, suggesting differences in hospital treatment did not substantially contribute to ethnic inequalities.
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影响因子：
9.3
作者：
Niedzwiedz, Claire L.;O'Donnell, Kate A.;Katikireddi, S. Vittal
通讯作者：
Katikireddi, S. Vittal
影响因子：
15.1
作者：
Irizar, Patricia;Pan, Daniel;Kapadia, Dharmi;Becares, Laia;Sze, Shirley;Taylor, Harry;Amele, Sarah;Kibuchi, Eliud;Divall, Pip;Gray, Laura J.;Nellums, Laura B.;Katikireddi, Srinivasa Vittal;Pareek, Manish
通讯作者：
Pareek, Manish
影响因子：
2.9
作者：
Henery P;Vasileiou E;Hainey KJ;Buchanan D;Harrison E;Leyland AH;Alexis T;Robertson C;Agrawal U;Ritchie L;Stock SJ;McCowan C;Docherty A;Kerr S;Marple J;Wood R;Moore E;Simpson CR;Sheikh A;Katikireddi SV
通讯作者：
Katikireddi SV
流行病学研究的链接行政数据引起的偏见：从注册到分析的概念框架。
影响因子：
13.6
作者：
Shaw, Richard J.;Harron, Katie L.;Pescarini, Julia M.;Pinto Junior, Elzo Pereira;Allik, Mirjam;Siroky, Andressa N.;Campbell, Desmond;Dundas, Ruth;Ichihara, Maria Yury;Leyland, Alastair H.;Barreto, Mauricio L.;Katikireddi, Srinivasa Vittal
通讯作者：
Katikireddi, Srinivasa Vittal
影响因子：
6.3
作者：
Leslie, Kirstin;Findlay, Beth;Ryan, Theresa;Green, Leonardo, I;Harvey, Ciaran;Whettlock, Alice E.;Bishop, Jen;Hardy, Vicki Ponce;Went, April;Wallace, Lesley;McLeod, Allan;Weir, Amanda;Marsh, Kimberly
通讯作者：
Marsh, Kimberly