The multifaceted genomic history of Ashaninka from Amazonian Peru

The multifaceted genomic history of Ashaninka from Amazonian Peru
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秘鲁亚马逊流域 Ashaninka 的多方面基因组历史

DOI:
10.1016/j.cub.2023.02.046
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发表时间:
2023
期刊:
影响因子:
9.2
通讯作者:
Montinaro, Francesco
Montinaro, Francesco
中科院分区:
生物学1区
文献类型:
--
作者:
Capodiferro, Marco Rosario;Chero Osorio, Ana María;Rambaldi Migliore, Nicola;Tineo Tineo, Dean Herman;Raveane, Alessandro;Xavier, Catarina;Bodner, Martin;Simão, Filipa;Ongaro, Linda;Montinaro, Francesco

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尽管地理位置至关重要,但从基因组学和古基因组学的角度来看,安第斯山脉和亚马逊河源头之间的亚马逊河西岸仍然没有得到充分研究,尽管可能含有必要的信息,以澄清当地土著群体的复杂遗传历史及其与附近地区的相互作用,1,2,3,4,5,6,7,8包括中美洲和加勒比地区。[12]针对这一关键区域,我们分析了来自亚马逊秘鲁的51个阿沙宁卡个体的全基因组图谱,观察到了意想不到的基因组变异程度。我们确定了至少两个具有独特基因组组成的阿沙宁卡亚群,这些亚群因外部混合物的程度和时间而不同,特别是来自安第斯山脉和太平洋沿岸的土著群体。在大陆范围内,阿沙宁卡人的祖先可能是从南锥体和大西洋海岸的贡献下,从东南部地区迁移到亚马逊雨林的土著群体的南北移民。这些祖先的种群在南美洲内陆多样化的地理区域中多样化,在安第斯山脉的东侧,与周围的沿海群体有差异的相互作用。在这个复杂的场景中,我们还揭示了属于阿拉瓦坎语系的今天阿沙宁卡人的祖先13与那些向北迁移到加勒比海的土著群体之间的严格联系,这些土著群体为岛上早期的陶瓷(沙拉)传统做出了贡献。
Despite its crucial location, the western side of Amazonia between the Andes and the source(s) of the Amazon River is still understudied from a genomic and archaeogenomic point of view, albeit possibly harboring essential information to clarify the complex genetic history of local Indigenous groups and their interactions with nearby regions,1,2,3,4,5,6,7,8including central America and the Caribbean.9,10,11,12Focusing on this key region, we analyzed the genome-wide profiles of 51 Ashaninka individuals from Amazonian Peru, observing an unexpected extent of genomic variation. We identified at least two Ashaninka subgroups with distinctive genomic makeups, which were differentially shaped by the degree and timing of external admixtures, especially with the Indigenous groups from the Andes and the Pacific coast. On a continental scale, Ashaninka ancestors probably derived from a south-north migration of Indigenous groups moving into the Amazonian rainforest from a southeastern area with contributions from the Southern Cone and the Atlantic coast. These ancestral populations diversified in the variegated geographic regions of interior South America, on the eastern side of the Andes, differentially interacting with surrounding coastal groups. In this complex scenario, we also revealed strict connections between the ancestors of present-day Ashaninka, who belong to the Arawakan language family,13and those Indigenous groups that moved further north into the Caribbean, contributing to the early Ceramic (Saladoid) tradition in the islands.14,15
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发表时间: 2005
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