Critical assessment of methods of protein structure prediction-Round VII.

Critical assessment of methods of protein structure prediction-Round VII.
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DOI:
10.1002/prot.21767
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发表时间:
2007
影响因子:
2.9
通讯作者:
Tramontano, Anna
Tramontano, Anna
中科院分区:
生物学4区
文献类型:
--
作者:
Moult, John;Fidelis, Krzysztof;Kryshtafovych, Andriy;Rost, Burkhard;Hubbard, Tim;Tramontano, Anna

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本文是对《蛋白质》杂志增刊的介绍,该杂志致力于第七届CASP实验,以评估蛋白质结构预测的最新进展。本文描述了实验的进行,包括预测的类别,并概述了评估和评估程序。重点是模型精度相对于通过了解单一最佳模板结构可获得的精度的改进;自动服务器产生的模型的精度向人类建模团队产生的模型的精度趋同;预测模型质量的方法的出现;以及这些方法的实际应用迅速增加。
This paper is an introduction to the supplemental issue of the journal PROTEINS, dedicated to the seventh CASP experiment to assess the state of the art in protein structure prediction. The paper describes the conduct of the experiment, the categories of prediction included, and outlines the evaluation and assessment procedures. Highlights are improvements in model accuracy relative to that obtainable from knowledge of a single best template structure; convergence of the accuracy of models produced by automatic servers toward that produced by human modeling teams; the emergence of methods for predicting the quality of models; and rapidly increasing practical applications of the methods.
DOI: 10.1002/prot.21769
发表时间: 2007-01-01
影响因子: 2.9
作者:
Kryshtafovych, Andriy;Fidelis, Krzysztof;Moult, John
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