Correlations of non-exercise activity thermogenesis to metabolic parameters in Japanese patients with type 2 diabetes.
Correlations of non-exercise activity thermogenesis to metabolic parameters in Japanese patients with type 2 diabetes.
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DOI：
10.1186/1758-5996-5-26
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发表时间：
2013-05-27
影响因子：
4.8
通讯作者：
Noda M
中科院分区：
文献类型：
--
作者：
Hamasaki H;Yanai H;Mishima S;Mineyama T;Yamamoto-Honda R;Kakei M;Ezaki O;Noda M
非运动性活动产热（NEAT）是指日常生活中除了积极的体育运动和抗阻训练之外，由于身体活动而产生的能量消耗。我们研究了 45 名患有 2 型糖尿病的受试者（22 名女性和 23 名男性），他们没有服用任何降血糖、抗高血压或降胆固醇药物，并使用根据身体活动纲要修改的原始调查问卷询问他们与 NEAT 相关的身体活动。我们研究了 NEAT 评分与体重、腰围、血压、葡萄糖和脂质代谢以及动脉僵硬度的关联。所有受试者的 NEAT 评分与血清胰岛素水平呈负相关（r = -0.42，P < 0.05）。 NEAT 评分还与女性腰围呈负相关（r = -0.509，P < 0.05），与女性高密度脂蛋白胆固醇水平（r = 0.494，P < 0.05）呈正相关，与血清胰岛素水平（r = -0.732，p < 0.005）、收缩压（r = -0.482，P < 0.05）呈负相关。腹部肥胖患者的舒张压（r = -0.538，P < 0.05）。此外，吸烟者的 NEAT 评分与脉搏波速度呈负相关（r = -0.719，P < 0.005）。研究表明，NEAT 与 2 型糖尿病患者的胰岛素敏感性、腰围、高密度脂蛋白胆固醇、血压和动脉粥样硬化标志物的改善相关。
Non-exercise activity thermogenesis (NEAT) is the energy expenditure due to physical activities besides active sports-like exercise and resistance training in daily life. We studied 45 subjects (22 women and 23 men) with type 2 diabetes who did not take any hypoglycemic, anti-hypertensive, or cholesterol-lowering agents and asked them about physical activity concerned with NEAT using an original questionnaire modified from a compendium of physical activities. We studied the association of the NEAT score to body weight, waist circumference, blood pressure, glucose and lipid metabolism, and arterial stiffness. The NEAT score was negatively correlated with serum insulin levels (r = -0.42, P < 0.05) in all subjects. The NEAT score was also negatively correlated with waist circumference (r = -0.509, P < 0.05) and positively correlated with high-density lipoprotein-cholesterol levels (r = 0.494, P < 0.05) in women, and negatively associated with serum insulin levels (r = -0.732, p < 0.005), systolic (r = -0.482, P < 0.05) and diastolic blood pressure (r = -0.538, P < 0.05) in patients with abdominal obesity. Furthermore, the NEAT score was negatively associated with pulse wave velocity (r = -0.719, P < 0.005) in smokers. The study demonstrated that NEAT is associated with amelioration in insulin sensitivity, waist circumference, high-density lipoprotein-cholesterol, blood pressure and the marker for atherosclerosis in patients with type 2 diabetes.
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影响因子：
7.1
作者：
SCHULZ, LO;SCHOELLER, DA
通讯作者：
SCHOELLER, DA
影响因子：
9.8
作者：
JONES, PJH;SCHOELLER, DA
通讯作者：
SCHOELLER, DA
影响因子：
5.9
作者：
Reaven, Gerald M.
通讯作者：
Reaven, Gerald M.
影响因子：
5.5
作者：
Seals, Douglas R.;Walker, Ashley E.;Lesniewski, Lisa A.
通讯作者：
Lesniewski, Lisa A.
DOI：
10.2174/1874192401004020089
发表时间：
2010-02-23
期刊：
The open cardiovascular medicine journal
影响因子：
--
作者：
Metsios, George S;Stavropoulos-Kalinoglou, Antonios;Kitas, George D
通讯作者：
Kitas, George D