A continuum model for skeletal muscle contraction at homogeneous finite deformations

A continuum model for skeletal muscle contraction at homogeneous finite deformations
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均匀有限变形下骨骼肌收缩的连续模型

DOI:
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发表时间:
2012
影响因子:
3.5
通讯作者:
Jonas Stålhand
Jonas Stålhand
中科院分区:
工程技术2区
文献类型:
--
作者:
Babak Sharifimajd;Jonas Stålhand

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在骨骼肌模型中,收缩力通常被假定为等长力乘以一组实验激励的函数,这些函数解释了肌肉的活动特性。虽然这种方法既灵活又简单,但它并不能自动保证热力学上的一致行为。相反,本文提出的连续介质力学模型是根据力学的基本原理导出的,并保证了耗散行为。此外,收缩力与摩擦离合器有关,摩擦离合器为骑行跨越桥梁提供了一个简单而明确的宏观模型。为了展示该模型的性能,专门针对兔胫骨前肌进行了标准实验。结果表明,该模型能够很好地捕捉到骨骼肌的重要特征。
The contractile force in skeletal muscle models is commonly postulated to be the isometric force multiplied by a set of experimentally motivated functions which account for the muscle’s active properties. Although both flexible and simple, this approach does not automatically guarantee a thermodynamically consistent behavior. In contrast, the continuum mechanical model proposed herein is derived from fundamental principles in mechanics and guarantees a dissipative behavior. Further, the contractile force is associated with a friction clutch which provides a simple and well-defined macroscopic model for cycling cross-bridges. To show the performance of the model, it is specialized to standard experiments for rabbit tibialis anterior muscle. The results show that the model is able to capture important characteristics of skeletal muscle.
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发表时间: 2004-11-01
影响因子: 1.4
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