Cold-chain food contamination as the possible origin of COVID-19 resurgence in Beijing.
Cold-chain food contamination as the possible origin of COVID-19 resurgence in Beijing.
复制标题
DOI：
10.1093/nsr/nwaa264
复制
发表时间：
2020-12
影响因子：
20.6
通讯作者：
COVID-19 Laboratory Testing Group
中科院分区：
文献类型：
--
作者：
Pang X;Ren L;Wu S;Ma W;Yang J;Di L;Li J;Xiao Y;Kang L;Du S;Du J;Wang J;Li G;Zhai S;Chen L;Zhou W;Lai S;Gao L;Pan Y;Wang Q;Li M;Wang J;Huang Y;Wang J;COVID-19 Field Response Group;COVID-19 Laboratory Testing Group
由SARS-CoV-2引起的COVID-19[1,2]在中国通过严格的非药物干预措施得到了控制。边境控制和检疫有效地防止了病毒通过受感染的旅行者传播，但其他传入和传播途径造成的死灰复燃风险仍不清楚，目前防止死灰复燃的战略可能存在缺陷。自7月以来，中国9个省份报告了从疫情持续国家进口的冷冻食品中存在SARS-CoV-2 RNA污染[3,4]。然而，没有强有力的证据表明COVID-19疫情是由环境-人类传播引起的。在这里，我们通过调查最近在北京再次出现的COVID-19，增加了这种传播的证据。2020年6月11日，北京一名患有发烧和咳嗽的52岁男子在56天无新发病例间隔后被诊断为COVID-19。无已知COVID-19病例接触史。6月12日，采用定量逆转录聚合酶链反应（qRT-PCR）对指示病例的112名密切接触者和从其去过的地方采集的242份环境样本进行了检测。所有密切接触者均呈阴性，但新发市场的两个环境样本呈SARS-CoV-2阳性。这导致了深入的调查，以确认XFDM在病毒传播中的作用。对与新冠病毒阳性环境样本接近的538名工作人员进行了检测，其中45名工作人员qRT-PCR检测呈阳性。
COVID-19, caused by SARS-CoV-2 [1, 2], has been contained in China through stringent non-pharmaceutical interventions. Border control and quarantine have effectively prevented the virus from being spread by infected travellers, but the risk of resurgence caused by other routes of introduction and transmission remains unclear, and current strategies to prevent resurgence could be flawed. Since July, SARS-CoV-2 RNA contaminations in frozen food imported from countries with ongoing epidemics have been reported in nine provinces in China [3, 4]. However, there is no robust evidence of COVID-19 outbreaks initiated by environmentto-human transmission. Here we add to evidence of such transmission by investigating the recent COVID-19 resurgence in Beijing. On 11 June 2020, a 52-year old man suffering from fever and cough was diagnosed with COVID-19 in Beijing, after a 56-day zero new case interval. He had no exposure history of known COVID-19 cases. On 12 June, 112 close contacts of the index case and 242 environmental samples collected from the places that he had visited were tested by quantitative reverse transcription polymerase chain reaction (qRT-PCR).All close contacts were negative, but two environmental samples from Xinfadi Market (XFDM) were positive for SARS-CoV-2. This led to in-depth investigation to confirm the role of XFDM in virus spread. A total of 538 employees from the booths that were close to the SARS-CoV-2-positive environmental samples were tested, and 45 were positive by qRT-PCR.
登录
查看更多内容
DOI：
10.1073/pnas.1919800117
发表时间：
2020-02-11
影响因子：
11.1
作者：
Di, Lin;Fu, Yusi;Wang, Jianbin
通讯作者：
Wang, Jianbin
影响因子：
6.1
作者：
Ren, Li-Li;Wang, Ye-Ming;Wang, Jian-Wei
通讯作者：
Wang, Jian-Wei
DOI：
10.1016/j.jgg.2020.10.002
发表时间：
2020-10-20
期刊：
Journal of genetics and genomics = Yi chuan xue bao
影响因子：
--
作者：
Xu Y;Kang L;Shen Z;Li X;Wu W;Ma W;Fang C;Yang F;Jiang X;Gong S;Zhang L;Li M
通讯作者：
Li M
影响因子：
28.3
作者：
Rambaut A;Holmes EC;O'Toole Á;Hill V;McCrone JT;Ruis C;du Plessis L;Pybus OG
通讯作者：
Pybus OG
影响因子：
--
作者：
Ceylan, Zafer;Meral, Raciye;Cetinkaya, Turgay
通讯作者：
Cetinkaya, Turgay