Does extended release methylphenidate help adults with hoarding disorder?: a case series.
Does extended release methylphenidate help adults with hoarding disorder?: a case series.
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缓释哌醋甲酯对患有囤积症的成年人有帮助吗？：案例系列。
DOI：
10.1097/jcp.0b013e318290115e
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发表时间：
2013
影响因子：
2.9
通讯作者：
Simpson,HelenBlair
中科院分区：
文献类型：
--
作者：
Rodriguez,CarolynI;BenderJr,James;Morrison,Samantha;Mehendru,Raveen;Tolin,David;Simpson,HelenBlair
Disorders, Fifth Edition (DSM-V), commonly self-report poor attention2, 3 and have significant impairments on objective measures of attention (eg, the Continuous Performance Test [CPT]). 4, 5 Problems with attention may contribute to difficulty making decisions and lead to the accumulation of clutter. 6 A single case report of an individual with compulsive HD and attention-deficit/hyperactivity disorder (ADHD) suggested that amphetamine salts may provide benefits in self-reported attention and some aspects of hoarding such as procrastination. 7 However, to our knowledge, no study has tested the effects of stimulants in individuals with HD without comorbid ADHD. Therefore, we tested if adjunctive methylphenidate extended release (MPH-ER), 8 a stimulant with proven efficacy in improving attention, can increase attention on both self-report and objective measures and decrease hoarding symptoms in individuals that met the proposed DSM-V criteria for HD1 but did not have comorbid ADHD. Four adults (age 18-50 years) who met the HD criteria proposed by Frost and Hartl9 (assessed by the Hoarding Rating ScaleYInterview [HRS-I] 10) and who had clinically significant hoarding (a Saving InventoryYRevised [SI-R] 11 score of Q40) were recruited from the community between April 2010 and July 2010. During the study, the proposed DSM-V criteria for HD were published, 1 and all subjects met these additional criteria (ie, hoarding symptoms not due to a medical condition [assessed by medical history and examination] and were not restricted to symptoms of another mental disease [assessed by Structured Clinical Interview for DSM-IV Disorders and psychiatric examination]). One patient had comorbid obsessive compulsive disorder (OCD), but the hoarding symptoms were clearly in dependent from the OCD (ie, mild symptoms of needing to count choir members to a certain number or else she did not ‘‘feel right’’). The institutional review board approved this study, and all subjects provided written informed consent. None met DSM-IV criteria for ADHD, but all reported at least moderate attention problems (an Adult Attention subscale score of Q8 on the ADHD Symptom Scale [ADHDSS] 12). Of the 4 subjects, 2 were on medications as shown in Table 1, but these medications were stable before study entry (12 weeks for serotonin reuptake inhibitors [SRIs] or serotonin and norepinephrine reuptake inhibitors [SNRIs] and 4 weeks for others). Subjects were excluded for current use of any type of stimulant medication or psychotherapy, comorbid psychiatric or medical conditions that increased the risk of TABLE
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影响因子：
4.1
作者：
Hartl, TL;Duffany, SR;Frost, RO
通讯作者：
Frost, RO
影响因子：
12.8
作者：
Steketee, Gail;Frost, Randy
通讯作者：
Frost, Randy
影响因子：
4.1
作者：
Frost, RO;Steketee, G;Grisham, J
通讯作者：
Grisham, J
影响因子：
4.1
作者：
Frost, RO;Hartl, TL
通讯作者：
Hartl, TL
强迫性囤积症的药物治疗。
影响因子：
3
作者：
S. Saxena
通讯作者：
S. Saxena