Anisocytosis Is Associated With Reduced Bone Marrow Activity Evaluated by Positron Emission Tomography.
Anisocytosis Is Associated With Reduced Bone Marrow Activity Evaluated by Positron Emission Tomography.
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通过正电子发射断层扫描评估，细胞大小不均与骨髓活性降低有关。
DOI：
10.1016/j.amjcard.2021.05.001
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发表时间：
2021
期刊：
影响因子：
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通讯作者：
McComsey,GraceA
中科院分区：
文献类型：
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作者：
Janus,ScottE;Al-Kindi,SadeerG;Hajjari,Jamal;Chami,Tarek;Avery,Ann;Labbato,Danielle;Smith,Cheryl;Sullivan,Claire;Hileman,CorrilynnO;McComsey,GraceA
红细胞异位或红细胞分布宽度（RDW）增加与心血管风险升高有关，特别是在冠状动脉疾病和心力衰竭患者中。1,2 .细胞异数症与全身炎症、氧化应激和铁代谢的标志物有关。然而，将RDW与心血管结局联系起来的机制尚不清楚。第二个模型显示RDW与平均骨髓SUV呈负相关（rho= - 0.32, p= 0.044），尽管模型1中加入了炎症生物标志物（IL6，高敏感性c反应蛋白）。本研究的局限性包括样本量小，单一RDW测量，未直接分析骨髓功能，以及可能的其他混杂因素（包括相当一部分男性和海洛因使用者）。
Anisocytosis or increased red blood cell distribution width (RDW) has been associated with an elevated cardiovascular risk, especially in patients with coronary artery disease and heart failure. 1, 2 Anisocytosis has been linked with markers of systemic inflammation, oxidative stress, and iron metabolism. 3 However, the mechanism linking RDW with cardiovascular outcomes remains unknown. A second model demonstrated RDW remained negatively correlated (rho=− 0.32, p= 0.044) with mean bone marrow SUV despite accounting Model 1 with the addition of biomarkers of inflammation (IL6, high sensitivity C-reactive protein). The limitations of our study include the small sample size, single RDW measurement, no direct analysis of bone marrow function, and possible other confounders (including significant portion of males and heroin users).
影响因子：
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作者：
Al-Kindi SG;Refaat M;Jayyousi A;Asaad N;Al Suwaidi J;Abi Khalil C
通讯作者：
Abi Khalil C
DOI：
10.1016/j.jcmg.2014.10.009
发表时间：
2015-03
期刊：
JACC. Cardiovascular imaging
影响因子：
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作者：
Emami H;Singh P;MacNabb M;Vucic E;Lavender Z;Rudd JH;Fayad ZA;Lehrer-Graiwer J;Korsgren M;Figueroa AL;Fredrickson J;Rubin B;Hoffmann U;Truong QA;Min JK;Baruch A;Nasir K;Nahrendorf M;Tawakol A
通讯作者：
Tawakol A
DOI：
10.1016/j.clnu.2010.03.001
发表时间：
2010-10
期刊：
Clinical nutrition (Edinburgh, Scotland)
影响因子：
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作者：
Semba RD;Patel KV;Ferrucci L;Sun K;Roy CN;Guralnik JM;Fried LP
通讯作者：
Fried LP