Definition of critical asthma syndromes.
Definition of critical asthma syndromes.
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DOI：
10.1007/s12016-013-8395-6
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发表时间：
2015-03
影响因子：
9.1
通讯作者：
Louie S
中科院分区：
文献类型：
--
作者：
Kenyon N;Zeki AA;Albertson TE;Louie S
因急性重度哮喘急性发作而紧急前往诊所和急诊室的情况太频繁了。现有的国家指南没有提出一致的或具体的建议，评估和治疗个别哮喘患者的呼吸窘迫。在这种情况下，我们提出了术语“危重哮喘综合征”（CAS）来描述任何儿童或成人谁是致命的哮喘的高风险。急性重度哮喘、难治性哮喘、哮喘持续状态和几乎致命的哮喘都描述了CAS，其中呼吸的压倒性工作导致的身体疲惫导致呼吸骤停和缺氧或相关并发症死亡。本补充材料的作者试图强调早期识别、及时和协调评估以及由经验丰富的医疗保健提供者团队在急诊科、医院和重症监护室治疗CAS的重要性。CAS不是重度持续性哮喘，在这种情况下，控制症状和预防加重是门诊慢性病管理的目标。作者在整个补充中讨论了这两个实体之间的区别，并详细阐述了危重患者护理中的重要考虑因素，包括要避免的常见错误。此外，在知识和临床经验方面的差距，在危重哮喘突出。知识差距包括缺乏对如何识别CAS的理解，如何协调和整合医院和门诊资源，何时进一步表型危重哮喘患者以促进有效治疗，以及如何预防未来急性加重。最后，CAS是复杂的事实，哮喘护理在不同的医疗机构是偶然的。我们建议初级保健医生及时将患者转诊至哮喘专家进行咨询，以减少急性加重的频率并预防CAS的发展。
Urgent visits to the clinic and emergency department for acute severe asthma exacerbations are all too frequent. Existing national guidelines do not present consistent or specific recommendations for the evaluation and treatment of individual asthma patients in respiratory distress. In this vein, we propose the term “critical asthma syndrome” (CAS) to describe any child or adult who is at high risk for fatal asthma. Acute severe asthma, refractory asthma, status asthmaticus, and near-fatal asthma all describe CAS where physical exhaustion from the overwhelming work of breathing leads to respiratory arrest and death from hypoxia or related complications. The authors of this supplement seek to emphasize the importance of early recognition, prompt and coordinated evaluation, and treatment of CAS in the emergency department, hospital, and intensive care units by experienced healthcare provider teams. CAS is not severe persistent asthma where control of symptoms and prevention of exacerbations are targets of chronic disease management in the outpatient setting. The authors address the distinctions between the two entities throughout the supplement, and elaborate on the considerations important in the care of a critically ill patient, including the common errors to avoid. In addition, gaps in knowledge and clinical experience in regards to critical asthma are highlighted. Knowledge gaps include a lack of understanding of how to recognize CAS, how to coordinate and integrate hospital and outpatient resources, when to further phenotype patients with critical asthma in order to facilitate effective treatment, and how to prevent future acute exacerbations. Lastly, CAS is complicated by the fact that asthma care in diverse healthcare settings is haphazard. We recommend that primary care physicians refer patients promptly to an asthma specialist for consultation to reduce the frequency of acute exacerbations and prevent the development of CAS.
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影响因子：
12.4
作者：
Amelink, M.;de Nijs, S. B.;Bel, E. H.
通讯作者：
Bel, E. H.
影响因子：
4.4
作者：
Kroegel, Claus
通讯作者：
Kroegel, Claus
患有哮喘的成年人的流行病学和结果，他们住院或死于2009年大流行性流感A（H1N1） - 加利福尼亚，2009年。
影响因子：
4.4
作者：
Mortensen E;Louie J;Pertowski C;Cadwell BL;Weiss E;Acosta M;Matyas BT
通讯作者：
Matyas BT
影响因子：
3.7
作者：
Patrawalla P;Kazeros A;Rogers L;Shao Y;Liu M;Fernandez-Beros ME;Shang S;Reibman J
通讯作者：
Reibman J
DOI：
10.1165/ajrcmb/3.5.507
发表时间：
1990-11-01
影响因子：
6.4
作者：
BREWSTER, CEP;HOWARTH, PH;ROCHE, WR
通讯作者：
ROCHE, WR