Corneal backscatter analysis by in vivo confocal microscopy: fellow eye comparison of small incision lenticule extraction and femtosecond laser-assisted LASIK.

Corneal backscatter analysis by in vivo confocal microscopy: fellow eye comparison of small incision lenticule extraction and femtosecond laser-assisted LASIK.
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DOI:
10.1155/2014/265012
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发表时间:
2014
影响因子:
1.9
通讯作者:
Yilmaz OF
Yilmaz OF
中科院分区:
医学4区
文献类型:
--
作者:
Agca A;Ozgurhan EB;Yildirim Y;Cankaya KI;Guleryuz NB;Alkin Z;Ozkaya A;Demirok A;Yilmaz OF

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目的。评价和比较小切口晶状体摘除术(SMILE)和飞秒激光辅助LASIK(FETO-LASIK)术中角膜前基质的后向散射。方法:研究方法。30名患者的60只眼被随机分成两组,一只眼接受微笑,另一只眼接受Femto-LASIK。术后1周、1、3、6个月行体内共聚焦显微镜检查。测量的主要结果是最大背向散射强度及其测量深度、瓣界面鲍曼膜下30 μm和浅上皮下150 μm处的背向散射光强度,以及瓣界面处折射颗粒的数量。结果。在所有术后随访中,SMILE组所有测量深度的平均背向散射光强度(LI)和最大背向散射光强度(LI)均高于Femto-LASIK组。1周、1个月和3个月的LI差异有统计学意义(P<0,05)。6个月时LI差异无统计学意义。在任何一次访问中,两组之间在瓣界面处的屈光颗粒数量没有差异。结论。与Femto-LASIK相比,评估微笑导致前基质中背向散射LI增加的结果。
Purpose. To evaluate and compare corneal backscatter from anterior stroma between small incision lenticule extraction (SMILE) and femtosecond laser-assisted LASIK (femto-LASIK). Methods. A cohort of 60 eyes of 30 patients was randomized to receive SMILE in one eye and femto-LASIK in the fellow eye. In vivo confocal microscopy was performed at 1 week and 1, 3, and 6 months after surgery. The main outcome measurements were maximum backscattered intensity and the depth from which it was measured, the backscattered light intensity 30 μm below Bowman's membrane at the flap interface and 150 μm below the superficial epithelium, and the number of refractive particles at the flap interface. Results. The mean backscattered light intensity (LI) at all measured depths and the maximum backscattered LI were higher in the SMILE group than the femto-LASIK group at all postoperative visits. LI differences at 1 week and 1- and 3-month visits were statistically significant (P < 0,05). LI differences at 6 months were not statistically significant. There was no difference in the number of refractive particles at the flap interface between the groups at any visit. Conclusions. SMILE results in increased backscattered LI in the anterior stroma when compared with femto-LASIK were evaluated.
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