Yeast systems biology: the challenge of eukaryotic complexity.
Yeast systems biology: the challenge of eukaryotic complexity.
复制标题
酵母系统生物学:真核复杂性的挑战。
DOI:
10.1007/978-1-61779-173-4_1
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发表时间:
2011
期刊:
影响因子:
--
通讯作者:
Castrillo JI
中科院分区:
文献类型:
--
作者:
Castrillo JI
In this chapter, we present an up-to-date view of the optimal characteristics of the yeastSaccharomyces cerevisiaeas a model eukaryote for systems biology studies, with main molecular mechanisms, biological networks, and sub-cellular organization essentially conserved in all eukaryotes, derived from a complex common ancestor. The existence of advanced tools for molecular studies together with high-throughput experimental and computational methods, most of them being implemented and validated in yeast, with new ones being developed, is opening the way to the characterization of the core modular architecture and complex networks essential to all eukaryotes. Selected examples of the latest discoveries in eukaryote complexity and systems biology studies using yeast as a reference model and their applications in biotechnology and medicine are presented.
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影响因子:
56.9
作者:
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通讯作者:
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影响因子:
64.5
作者:
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通讯作者:
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影响因子:
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作者:
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DOI:
10.1093/bfgp/elp002
发表时间:
2009-01-01
期刊:
Briefings in Functional Genomics & Proteomics
影响因子:
--
作者:
Meyer, Markus;Vilardell, Josep
通讯作者:
Vilardell, Josep
影响因子:
10.5
作者:
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通讯作者:
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