Resting state functional connectivity of the ventral auditory pathway in musicians with absolute pitch

Resting state functional connectivity of the ventral auditory pathway in musicians with absolute pitch
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具有绝对音高的音乐家腹侧听觉通路的静息状态功能连接

DOI:
10.1002/hbm.23637
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发表时间:
2017
影响因子:
4.8
通讯作者:
T. Knösche
T. Knösche
中科院分区:
医学2区
文献类型:
--
作者:
Seung;T. Knösche

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绝对音高(AP)是在没有外界参考的情况下识别音调音色的能力,为人类听觉系统提供了一个独特的模型(Zatorre: Nat Neurosci 6() 692-695)。在之前的一项研究中(Kim和Knösche: Hum Brain Mapp() 3486-3501),我们发现患有AP的音乐家右平面极(PP)的皮质内髓鞘形成增强,这可能是音高色度信息感知加工的潜在部位。我们推测,在“双通路假说”的背景下,这个启动腹侧听觉通路的区域可能在AP过程的感知阶段至关重要,该假说表明腹侧通路在处理与听觉对象身份相关的非空间信息方面的作用(Rauschecker: Eur J Neurosci 41() 579-585)。为了验证我们对腹侧通路的猜想,我们使用功能性磁共振成像(fMRI)对不同程度AP的音乐家进行了静息状态功能连接(RSFC)研究。如果我们的假设是正确的,那么通过腹侧通路的RSFC在AP音乐家中预计会更强,而通过背侧通路的RSFC则没有预测到这种群体效应。在目前的数据中,我们发现患有AP的音乐家的右侧PP和双侧前腹侧听觉皮层之间的RSFC更大。相比之下,我们没有发现患有和不患有AP的音乐家的颞平面(PT)的RSFC有任何组间差异。我们认为这些发现支持了我们关于腹侧通路在AP识别中的关键作用的猜想。中国生物医学工程学报(英文版),2017。©2017 Wiley期刊公司
Absolute pitch (AP) is the ability to recognize pitch chroma of tonal sound without external references, providing a unique model of the human auditory system (Zatorre: Nat Neurosci 6 ( ) 692–695). In a previous study (Kim and Knösche: Hum Brain Mapp ( ) 3486–3501), we identified enhanced intracortical myelination in the right planum polare (PP) in musicians with AP, which could be a potential site for perceptional processing of pitch chroma information. We speculated that this area, which initiates the ventral auditory pathway, might be crucially involved in the perceptual stage of the AP process in the context of the “dual pathway hypothesis” that suggests the role of the ventral pathway in processing nonspatial information related to the identity of an auditory object (Rauschecker: Eur J Neurosci 41 ( ) 579–585). To test our conjecture on the ventral pathway, we investigated resting state functional connectivity (RSFC) using functional magnetic resonance imaging (fMRI) from musicians with varying degrees of AP. Should our hypothesis be correct, RSFC via the ventral pathway is expected to be stronger in musicians with AP, whereas such group effect is not predicted in the RSFC via the dorsal pathway. In the current data, we found greater RSFC between the right PP and bilateral anteroventral auditory cortices in musicians with AP. In contrast, we did not find any group difference in the RSFC of the planum temporale (PT) between musicians with and without AP. We believe that these findings support our conjecture on the critical role of the ventral pathway in AP recognition. Hum Brain Mapp 38:3899–3916, 2017. © 2017 Wiley Periodicals, Inc.
DOI: 10.1093/cercor/bhr099
发表时间: 2012-01-01
期刊: CEREBRAL CORTEX
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发表时间: 2014
期刊: Cerebral cortex
影响因子: 3.7
作者:
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