Social factors matter in cancer risk and survivorship.
Social factors matter in cancer risk and survivorship.
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DOI：
10.1007/s10552-018-1043-y
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发表时间：
2018-07
期刊：
影响因子：
--
通讯作者：
Schmitz KH
中科院分区：
文献类型：
--
作者：
Dean LT;Gehlert S;Neuhouser ML;Oh A;Zanetti K;Goodman M;Thompson B;Visvanathan K;Schmitz KH
鉴于肿瘤生物学和遗传变异的差异并不能完全解释持续存在的黑人/白色人乳腺癌死亡率差异，因此在包括乳腺癌在内的癌症连续体中，需要更多地关注社会因素，如种族/民族、社会经济地位等。在这篇评论中，我们使用乳腺癌风险评估和生存率的例子来证明未能适当地将社会因素纳入研究的设计，招募和分析中，导致错过了减少持续癌症差异的机会。结论为如何更好地记录和使用癌症研究和护理中的社会因素信息提供了建议：（1）增加教育和意识，了解在临床研究中纳入社会因素的重要性;（2）通过将其纳入期刊指南和报告分层结果来改善社会因素的测试和记录;以及（3）包括社会因素，以完善评估癌症风险和分配癌症护理的现有工具。实施建议的改变将使干预措施的设计和实施更加有效，并通过考虑癌症患者生活和接受治疗的社会和环境背景来消除癌症差异。
Greater attention to social factors, such as race/ethnicity, socioeconomic position, and others, are needed across the cancer continuum, including breast cancer, given differences in tumor biology and genetic variants have not completely explained the persistent Black/White breast cancer mortality disparity. In this commentary, we use examples in breast cancer risk assessment and survivorship to demonstrate how the failure to appropriately incorporate social factors into the design, recruitment, and analysis of research studies has resulted in missed opportunities to reduce persistent cancer disparities. The conclusion offers recommendations for how to better document and use information on social factors in cancer research and care by (1) increasing education and awareness about the importance of inclusion of social factors in clinical research; (2) improving testing and documentation of social factors by incorporating them into journal guidelines and reporting stratified results; and (3) including social factors to refine extant tools that assess cancer risk and assign cancer care. Implementing the recommended changes would enable more effective design and implementation of interventions and work toward eliminating cancer disparities by accounting for the social and environmental contexts in which cancer patients live and are treated.
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影响因子：
2.1
作者：
Adams-Campbell, Lucile L.;Makambi, Kepher H.;Rosenberg, Lynn
通讯作者：
Rosenberg, Lynn
DOI：
10.1136/bmj.e70
发表时间：
2012-01-30
期刊：
BMJ (Clinical research ed.)
影响因子：
--
作者：
Fong DY;Ho JW;Hui BP;Lee AM;Macfarlane DJ;Leung SS;Cerin E;Chan WY;Leung IP;Lam SH;Taylor AJ;Cheng KK
通讯作者：
Cheng KK
影响因子：
12.7
作者：
Cochran, SD;Mays, VM;White, J
通讯作者：
White, J
影响因子：
3.8
作者：
Brown, Justin C.;Huedo-Medina, Tania B.;Johnson, Blair T.
通讯作者：
Johnson, Blair T.
影响因子：
--
作者：
Brooks, Sandra E.;Muller, Carolyn Y.;McCaskill-Stevens, Worta
通讯作者：
McCaskill-Stevens, Worta