Feeding regulation in Drosophila.

Feeding regulation in Drosophila.
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DOI:
10.1016/j.conb.2014.05.008
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发表时间:
2014-12
影响因子:
5.7
通讯作者:
Scott K
Scott K
中科院分区:
医学2区
文献类型:
--
作者:
Pool AH;Scott K

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神经调质在基于环境线索和内部需求调整动物行为中起关键作用。在这里,我们回顾了果蝇摄食行为的调节,以说明神经调节剂如何实现行为可塑性。最近的研究在确定将果蝇的代谢需求转化为神经内分泌和神经调节状态变化的分子和细胞机制方面取得了快速进展。这些神经调质反过来促进或抑制离散的进食行为子程序。这篇综述强调了生理需求,神经调节状态和喂养决策之间的联系。
Neuromodulators play a key role in adjusting animal behavior based on environmental cues and internal needs. Here, we review the regulation of Drosophila feeding behavior to illustrate how neuromodulators achieve behavioral plasticity. Recent studies have made rapid progress in determining molecular and cellular mechanisms that translate the metabolic needs of the fly into changes in neuroendocrine and neuromodulatory states. These neuromodulators in turn promote or inhibit discrete feeding behavioral subprograms. This review highlights the links between physiological needs, neuromodulatory states, and feeding decisions.
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