Relative impact of Axis I mental disorders on quality of life among adults in the community.

Relative impact of Axis I mental disorders on quality of life among adults in the community.
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DOI:
10.1016/j.jad.2011.01.010
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发表时间:
2011-06
影响因子:
6.6
通讯作者:
Chen, Henian
Chen, Henian
中科院分区:
医学2区
文献类型:
--
作者:
Guan, Bingqing;Deng, Yunlong;Cohen, Patricia;Chen, Henian

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Little is known about the relative impact of different mental disorders on adult quality of life (QOL). This study estimated associations between several mental disorders and QOL in a representative American community sample. The QOL instrument was administered to 640 adult participants in the Children in the Community Study, a population-based longitudinal study. DSM-Axis I and Axis II mental disorder diagnoses were assessed by psychiatric interview. Poorer QOL was strongly associated with having a mood disorder, especially major depression disorder (MDD) (effect size, ES = −0.57, p <0.01), whereas poorer quality social relationships were associated with having dysthymia and bipolar disorders (ES = −0.92, p<0.01; ES = −0.80, p <0.05, respectively). Most anxiety disorders were not independently related to QOL with the exception of post traumatic stress disorder (PTSD), which was significantly related to poorer physical health (ES = −0.78, p <0.01) and psychological well-being (ES = −0.73, p <0.01) and to less overall QOL (ES = −0.57, p <0.01). MDD and PTSD are independently related to impaired QOL and dysthymia and bipolar disorder negatively influence social relationships.
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