Parallel processing of olfactory memories in Drosophila.

Parallel processing of olfactory memories in Drosophila.
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DOI:
10.4161/fly.4.2.11445
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发表时间:
2010-04
期刊:
Fly
影响因子:
1.2
通讯作者:
Dubnau JT
Dubnau JT
中科院分区:
生物学4区
文献类型:
--
作者:
Blum A;Dubnau JT

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One of the hallmarks of both memory and the underlying synaptic plasticity is that they each rely on short-lived and longer-lived forms. Short-lived memory is thought to rely on modification to existing proteins, whereas long-term memory requires induction of new gene expression. The most common view is that these two processes rely on signaling mechanisms within the same neurons. We recently demonstrated a dissection of the signaling requirements for short and long-lived memory into distinct sets of neurons. Using an aversive olfactory conditioning task in Drosophila, we found that cAMP signaling in different neuron cell types is sufficient to support short or long-term memory independently.
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