Stimulus Perception by Histidine Kinases
Stimulus Perception by Histidine Kinases
复制标题
组氨酸激酶的刺激感知
DOI:
10.1002/9781119004813.ch25
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发表时间:
2016
期刊:
影响因子:
--
通讯作者:
Heermann
中科院分区:
文献类型:
--
作者:
Schramke;Heermann
The adaptation to changing environments is especially challenging for unicellular organisms. Many parameters like availability of nutrients, concentration of different ions, osmolarity, temperature, and cell density have to be permanently sensed to allow a cellular response. In bacteria, the most common way to adapt to different environments is via two‐component signal transduction. A prototypical two‐component system consists of a histidine kinase, which autophosphorylates upon stimulus perception, and a response regulator mediating the cellular response. Despite extensive research, in most cases the stimulus sensed by the histidine kinase is not yet known. However, there are some well‐characterised histidine kinases, for which the molecular mechanism of stimulus perception and signalling process is already explored, and these are described in detail in this chapter.
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