The prevalence of helicobacter pylori among dyspeptic patients in an earthquake-stricken area.

The prevalence of helicobacter pylori among dyspeptic patients in an earthquake-stricken area.
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地震袭击区域的消化不良患者中幽门螺杆菌的患病率。

DOI:
10.6061/clinics/2015(01)12
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发表时间:
2015-01
期刊:
Clinics (Sao Paulo, Brazil)
影响因子:
--
通讯作者:
Kemik O
Kemik O
中科院分区:
其他
文献类型:
--
作者:
Suvak B;Dulger AC;Suvak O;Aytemiz E;Kemik O

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幽门螺杆菌是一种革兰氏阴性、螺旋形、产尿素酶的细菌,具有多个单极鞭毛。人类是H. pylori;然而,没有关于H.幽门螺杆菌的消化不良患者谁经历了自然灾害。因此,本研究的目的是检查H。幽门螺杆菌在消化不良患者谁幸存最近的自然灾害,并比较灾前和灾后时期的数据。2011年12月至2012年2月(地震后一个月),209名接受胃镜检查的消化不良患者被纳入研究。为了进行微生物鉴定,在含有尿素和pH指示剂的培养基中检测了209名患有消化不良的灾难幸存者的胃活检材料的尿素酶活性。并将所得结果与前一年同期同一城市消化不良患者的灾前数据进行比较。此外,目前的H.在2014年1月至2014年5月期间,对139名消化不良患者的幽门螺杆菌患病率进行了评估。我们发现H.灾难幸存者消化不良组与灾难前消化不良组比较,pylori水平差异有显著性(p<0.005)。有趣的是,目前的H。pylori感染率灾前和灾后均显著高于灾后(p<0.005)。这些结果表明,最近的地震可能有助于H。灾区居民幽门螺杆菌感染情况。这些数据也突出了异常高的H。消化不良患者的幽门螺杆菌患病率。区域差异需要进一步分析。
Helicobacter pylori is a gram-negative, spiral-shaped, urease-producing bacterium with multiple unipolar flagella. Humans are a major reservoir for H. pylori; however, there are no data on the prevalence of H. pylori among dyspeptic patients who have experienced natural disasters. Therefore, the aim of this study was to examine the prevalence of H. pylori in dyspeptic patients who survived a recent natural disaster and to compare the data between the pre-disaster and post-disaster periods. Between December 2011 and February 2012 (∼ one month following an earthquake), 209 dyspeptic patients who underwent gastroscopy were included in the study. For microorganism identification, gastric biopsy materials from the 209 disaster survivors with dyspeptic complaints were tested for urease activity in a medium containing urea and a pH indicator. The obtained results were compared with pre-disaster data from dyspeptic patients in the same city during the corresponding period of the previous year. Furthermore, the current H. pylori prevalence was evaluated among 139 dyspeptic patients between January 2014 and May 2014. We found a significantly higher prevalence of H. pylori in disaster survivors with dyspepsia compared with dyspeptic patients in the pre-disaster period (p<0.005). Interestingly, the current H. pylori prevalence was found to be significantly higher than the prevalence in both the disaster and pre-disaster periods (p<0.005). These results suggest that a recent earthquake could contribute to the development of H. pylori infection in subjects who live in the disaster-stricken area. These data also highlight the exceptionally high H. pylori prevalence in dyspeptic patients. Regional variations require further analyses.
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发表时间: 2013-04-01
影响因子: 6.3
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Kanno, Takeshi;Iijima, Kastunori;Shimosegawa, Tooru
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