Survey of hepatitis E virus in pork products and pig stools in Nakhon Pathom Province, Thailand.
Survey of hepatitis E virus in pork products and pig stools in Nakhon Pathom Province, Thailand.
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DOI：
10.1002/vms3.854
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发表时间：
2022-09
影响因子：
1.7
通讯作者：
中科院分区：
文献类型：
--
作者：
Hepatitis E virus (HEV) is an important public health threat resulting in more than 3 million symptomatic cases and 70,000 deaths annually. HEV is classified into at least eight genotypes, and five are associated with human infection. Genotypes 1 and 2 primarily affect humans, whereas genotypes 3 and 4 circulate in both humans and swine and are considered zoonotic viruses. Previous studies in Central Thailand have reported human HEV isolates with high similarity to swine strains and high seroprevalence in pigs, suggesting the potential for pig‐to‐human transmission. This study aimed to detect and analyse HEV in pork products and pig stools collected from local markets and pig farms in Nakhon Pathom Province in Central Thailand. A total of 177 pig stool and 214 pork product samples were detected for HEV by using RT–PCR amplification. Next, nucleotide sequencing and phylogenetic analysis were performed. We found one sample of pork products (1/214, 0.5%), which was a pig liver sample (1/51, 2.0%), and 49 HEV‐positive samples in pig stools (49/177, 27.7%). Phylogenetic analysis showed that all these HEV sequences belonged to genotype 3, with a high correlation between our samples and HEV from humans and swine was previously reported in Thailand. This study suggested that the consumption of poorly sanitized or uncooked animal meat or food and frequent exposure to pig stools may be risk factors for HEV infections in humans. Previous studies in Central Thailand have reported human HEV isolates with high similarity to swine strains and high seroprevalence in pigs, suggesting the potential for pig‐to‐human transmission. This study aimed to detect and analyze HEV in pork products and pig stools collected from local markets and pig farms in Central Thailand. We found one sample of pork products (1/214, 0.5%), which was a pig liver sample (1/51, 2.0%) and 49 HEV‐positive samples in pig stools (49/177, 27.7%). Phylogenetic analysis showed that all these HEV sequences belonged to genotype 3, with high correlation between our samples and HEV from humans and swine previously reported in Thailand.
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影响因子：
3.1
作者：
Poovorawan, Kittiyod;Jitmitrapab, Salyavit;Poovorawan, Yong
通讯作者：
Poovorawan, Yong
影响因子：
12.7
作者：
Siripanyaphinyo, Uamporn;Laohasinnarong, Dusit;Sawanpanyalert, Pathom
通讯作者：
Sawanpanyalert, Pathom
养猪场对丙型肝炎病毒的感染动态和持续性 - 综述。
影响因子：
3.4
作者：
Meester M;Tobias TJ;Bouwknegt M;Kusters NE;Stegeman JA;van der Poel WHM
通讯作者：
van der Poel WHM
影响因子：
11.8
作者：
Boccia, Delia;Guthmann, Jean-Paul;Guerin, Philippe Jean
通讯作者：
Guerin, Philippe Jean
影响因子：
3.8
作者：
Feagins, A. R.;Opriessnig, T.;Meng, X-J.
通讯作者：
Meng, X-J.