Mycomedicine: A Unique Class of Natural Products with Potent Anti-tumour Bioactivities.
Mycomedicine: A Unique Class of Natural Products with Potent Anti-tumour Bioactivities.
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Mycommedicine：一类独特的天然产物，具有有效的抗肿瘤生物活性
DOI：
10.3390/molecules26041113
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发表时间：
2021-02-19
期刊：
影响因子：
--
通讯作者：
Xu H
中科院分区：
文献类型：
--
作者：
Dai R;Liu M;Nik Nabil WN;Xi Z;Xu H
Mycomedicine is a unique class of natural medicine that has been widely used in Asian countries for thousands of years. Modern mycomedicine consists of fruiting bodies, spores, or other tissues of medicinal fungi, as well as bioactive components extracted from them, including polysaccharides and, triterpenoids, etc. Since the discovery of the famous fungal extract, penicillin, by Alexander Fleming in the late 19th century, researchers have realised the significant antibiotic and other medicinal values of fungal extracts. As medicinal fungi and fungal metabolites can induce apoptosis or autophagy, enhance the immune response, and reduce metastatic potential, several types of mushrooms, such as Ganoderma lucidum and Grifola frondosa, have been extensively investigated, and anti-cancer drugs have been developed from their extracts. Although some studies have highlighted the anti-cancer properties of a single, specific mushroom, only limited reviews have summarised diverse medicinal fungi as mycomedicine. In this review, we not only list the structures and functions of pharmaceutically active components isolated from mycomedicine, but also summarise the mechanisms underlying the potent bioactivities of several representative mushrooms in the Kingdom Fungi against various types of tumour.
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DOI：
10.1590/s1807-59322011001200021
发表时间：
2011
期刊：
Clinics (Sao Paulo, Brazil)
影响因子：
--
作者：
Novaes MR;Valadares F;Reis MC;Gonçalves DR;Menezes Mda C
通讯作者：
Menezes Mda C
DOI：
10.1016/j.bbagen.2010.03.016
发表时间：
2010-07-01
影响因子：
3
作者：
Endo, Masahiro;Beppu, Hidehiko;Matsui, Taei
通讯作者：
Matsui, Taei
影响因子：
2.8
作者：
Gao, YH;Zhou, SF;Dai, XH
通讯作者：
Dai, XH
影响因子：
1.7
作者：
ADACHI, Y;OHNO, N;YADOMAE, T
通讯作者：
YADOMAE, T
影响因子：
3.7
作者：
Chiu LY;Hu ME;Yang TY;Hsin IL;Ko JL;Tsai KJ;Sheu GT
通讯作者：
Sheu GT