Fear of Falling Does Not Influence Dual-Task Gait Costs in People with Parkinson's Disease: A Cross-Sectional Study.
Fear of Falling Does Not Influence Dual-Task Gait Costs in People with Parkinson's Disease: A Cross-Sectional Study.
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DOI：
10.3390/s22052029
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发表时间：
2022-03-05
期刊：
影响因子：
--
通讯作者：
Zipprich HM
中科院分区：
文献类型：
--
作者：
Prell T;Uhlig M;Derlien S;Maetzler W;Zipprich HM
认知缺陷和跌倒恐惧（FOF）都可以影响帕金森病（PD）的步态模式。虽然认知缺陷有助于双任务（DT）条件下的步态变化，目前还不清楚FOF是否也影响步态变化，同时执行认知任务。在这里，我们的目的是探索PD中FOF和DT成本之间的关联，我们还描述了FOF，认知和步态参数之间的关联，在单任务和DT。在40例PD患者中，评估了运动症状（MDS修订版的统一帕金森病评定量表，Hoehn和Yahr）、FOF（国际福尔斯疗效量表）和蒙特利尔认知评估（莫卡）。时空步态参数记录与一个经过验证的移动的步态分析系统与惯性测量单元在每只脚，而病人走在一个50米的走廊在他们的首选速度下单任务和DT条件。在单任务条件下，步长（β = 0.798）和空间变异性（β = 0.202）与FOF相关（校正R2 = 0.19，p < 0.001），而莫卡与时间变异性仅弱相关（校正R2 = 0.05，p < 0.001）。在DT条件下，速度，步幅和节奏下降，而空间变异性，时间变异性和步幅持续时间增加，速度的最大效应量。步长（β = 0.42）和年龄（β = 0.58）的DT成本解释了18%的莫卡方差。然而，FOF与步态参数的DT成本无关。行走时增加认知任务可能会加重PD患者的步态困难。然而，FOF似乎并没有对步态的双重任务成本产生相关影响。
Cognitive deficits and fear of falling (FOF) can both influence gait patterns in Parkinson’s disease (PD). While cognitive deficits contribute to gait changes under dual-task (DT) conditions, it is unclear if FOF also influences changes to gait while performing a cognitive task. Here, we aimed to explore the association between FOF and DT costs in PD, we additionally describe associations between FOF, cognition, and gait parameters under single-task and DT. In 40 PD patients, motor symptoms (MDS-revised version of the Unified Parkinson’s Disease Rating Scale, Hoehn and Yahr), FOF (Falls Efficacy Scale International), and Montreal Cognitive Assessment (MoCA) were assessed. Spatiotemporal gait parameters were recorded with a validated mobile gait analysis system with inertial measurement units at each foot while patients walked in a 50 m hallway at their preferred speed under single-task and DT conditions. Under single-task conditions, stride length (β = 0.798) and spatial variability (β = 0.202) were associated with FOF (adjusted R2 = 0.19, p < 0.001) while the MoCA was only weakly associated with temporal variability (adjusted R2 = 0.05, p < 0.001). Under DT conditions, speed, stride length, and cadence decreased, while spatial variability, temporal variability, and stride duration increased with the largest effect size for speed. DT costs of stride length (β = 0.42) and age (β = 0.58) explained 18% of the MoCA variance. However, FOF was not associated with the DT costs of gait parameters. Gait difficulties in PD may exacerbate when cognitive tasks are added during walking. However, FOF does not appear to have a relevant effect on dual-task costs of gait.
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影响因子：
3.7
作者：
Hass CJ;Malczak P;Nocera J;Stegemöller EL;Wagle Shukla A;Malaty I;Jacobson CE 4th;Okun MS;McFarland N
通讯作者：
McFarland N
DOI：
10.1097/npt.0000000000000090
发表时间：
2015-07
期刊：
Journal of neurologic physical therapy : JNPT
影响因子：
--
作者：
Fritz NE;Cheek FM;Nichols-Larsen DS
通讯作者：
Nichols-Larsen DS
影响因子：
2.4
作者：
Donath, Lars;Faude, Oliver;Mundermann, Annegret
通讯作者：
Mundermann, Annegret
影响因子：
3.4
作者：
Gassner, Heiko;Marxreiter, Franz;Klucken, Jochen
通讯作者：
Klucken, Jochen
影响因子：
9.9
作者：
Dalrymple-Alford, J. C.;MacAskill, M. R.;Anderson, T. J.
通讯作者：
Anderson, T. J.