Population genetic structure in Indian Austroasiatic speakers: the role of landscape barriers and sex-specific admixture.
Population genetic structure in Indian Austroasiatic speakers: the role of landscape barriers and sex-specific admixture.
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DOI：
10.1093/molbev/msq288
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发表时间：
2011-02
影响因子：
10.7
通讯作者：
Kivisild T
中科院分区：
文献类型：
--
作者：
Chaubey G;Metspalu M;Choi Y;Mägi R;Romero IG;Soares P;van Oven M;Behar DM;Rootsi S;Hudjashov G;Mallick CB;Karmin M;Nelis M;Parik J;Reddy AG;Metspalu E;van Driem G;Xue Y;Tyler-Smith C;Thangaraj K;Singh L;Remm M;Richards MB;Lahr MM;Kayser M;Villems R;Kivisild T
目前定居在南亚和东南亚的南亚语系（AA）的地理起源和传播时间仍然存在争议。两个竞争的假设，都假设一个流行的组成部分，语言的传播，已经提出。第一种假设认为，南亚语系的人起源于东南亚，后来在新石器时代扩散到南亚，而第二种假设则主张该语系起源于新石器时代之前，并从南亚扩散。为了测试这两种替代模型，本研究将单亲遗传标记与来自核基因组的610，000个常见单核苷酸多态性位点的分析相结合。印度AA扬声器有高频率的Y染色体单倍群O2 a;我们的研究结果表明，这个单倍群有显着较高的多样性和合并时间（17-28万年前）在东南亚，强烈支持第一个两个假设。然而，主成分和“结构样”的常染色体基因座分析的结果也表明，在印度的AA扬声器的人口历史更为复杂，其特征在于由两个祖先组成部分，一个代表的Y染色体和EDAR结果的模式和其他线粒体DNA多样性和基因组结构。我们建议，AA扬声器在印度今天来自东南亚的分散，其次是广泛的性别特异性混合与当地印度人口。
The geographic origin and time of dispersal of Austroasiatic (AA) speakers, presently settled in south and southeast Asia, remains disputed. Two rival hypotheses, both assuming a demic component to the language dispersal, have been proposed. The first of these places the origin of Austroasiatic speakers in southeast Asia with a later dispersal to south Asia during the Neolithic, whereas the second hypothesis advocates pre-Neolithic origins and dispersal of this language family from south Asia. To test the two alternative models, this study combines the analysis of uniparentally inherited markers with 610,000 common single nucleotide polymorphism loci from the nuclear genome. Indian AA speakers have high frequencies of Y chromosome haplogroup O2a; our results show that this haplogroup has significantly higher diversity and coalescent time (17–28 thousand years ago) in southeast Asia, strongly supporting the first of the two hypotheses. Nevertheless, the results of principal component and “structure-like” analyses on autosomal loci also show that the population history of AA speakers in India is more complex, being characterized by two ancestral components—one represented in the pattern of Y chromosomal and EDAR results and the other by mitochondrial DNA diversity and genomic structure. We propose that AA speakers in India today are derived from dispersal from southeast Asia, followed by extensive sex-specific admixture with local Indian populations.
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影响因子：
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作者：
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