Single B cell antibody technologies.
Single B cell antibody technologies.
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DOI:
10.1016/j.nbt.2011.03.014
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发表时间:
2011-09
影响因子:
5.4
通讯作者:
Tiller T
中科院分区:
文献类型:
--
作者:
Tiller T
Monoclonal antibodies (mAbs) are arguably the most significant class of biologics for use as pharmaceuticals and diagnostics. Many technological concepts exist for the generation and identification of therapeutically relevant mAbs, including the isolation and cloning of immunoglobulin (Ig) encoding genes from single B-lineage cells. This review summarizes various single B cell approaches and describes their use for the discovery of mAbs with potential therapeutic values or in basic research.
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影响因子:
32.4
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Isnardi I;Ng YS;Srdanovic I;Motaghedi R;Rudchenko S;von Bernuth H;Zhang SY;Puel A;Jouanguy E;Picard C;Garty BZ;Camcioglu Y;Doffinger R;Kumararatne D;Davies G;Gallin JI;Haraguchi S;Day NK;Casanova JL;Meffre E
通讯作者:
Meffre E
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Jiang, XiuPing;Suzuki, Hirotatsu;Nakano, Hideo
通讯作者:
Nakano, Hideo
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2.2
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Battye, FL;Light, A;Tarlinton, DM
通讯作者:
Tarlinton, DM
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作者:
EMBLETON, MJ;GOROCHOV, G;WINTER, G
通讯作者:
WINTER, G
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82.9
作者:
Jin, Aishun;Ozawa, Tatsuhiko;Muraguchi, Atsushi
通讯作者:
Muraguchi, Atsushi