The prevalence of retinal vein occlusion: pooled data from population studies from the United States, Europe, Asia, and Australia.
The prevalence of retinal vein occlusion: pooled data from population studies from the United States, Europe, Asia, and Australia.
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DOI：
10.1016/j.ophtha.2009.07.017
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发表时间：
2010-02
期刊：
影响因子：
13.7
通讯作者：
International Eye Disease Consortium
中科院分区：
文献类型：
--
作者：
Rogers S;McIntosh RL;Cheung N;Lim L;Wang JJ;Mitchell P;Kowalski JW;Nguyen H;Wong TY;International Eye Disease Consortium
总结美国、欧洲、亚洲和澳大利亚的视网膜静脉闭塞（RVO）患病率研究。使用基于个体群体的数据进行汇总分析。来自世界各地基于人群的研究的个体参与者数据已经从眼底照片中确定了RVO。每项研究都提供了按年龄、性别和种族划分的分支RVO和中心RVO的数据。患病率直接按2008年世界30岁及以上人口的年龄和性别标准化。估计是通过研究计算的，在汇总后，按种族计算。总结估计包括通过双眼≥2视野眼底照片评估RVO的研究。任何RVO、CRVO或BRVO。合并的汇总数据包含来自15项研究的68,751人，参与者的年龄从30岁到101岁不等。在对11项评估双眼≥2个眼底野的研究（n=49,869）的分析中，任何RVO的年龄和性别标准化患病率为5.20 / 1000（置信区间[CI]， 4.40-5.99）， BRVO为4.42 / 1000 (CI, 3.65-5.19)， CRVO为0.80 / 1000 （CI, 0.61-0.99）。患病率因种族/民族而异，并随年龄增长而增加，但因性别而无差异。年龄和性别标准化的RVO患病率在白人（5项研究）中为3.7 / 1000 (CI, 2.8-4.6)，在黑人（1项研究）中为3.9 / 1000 (CI, 1.8-6.0)，在亚洲（6项研究）中为5.7 / 1000 (CI, 4.5-6.8)，在西班牙裔（3项研究）中为6.9 / 1000 （CI, 5.7 - 8.3）。所有种族人群中CRVO的患病率均低于BRVO。根据这些数据，估计有1640万（CI, 13.9 - 18.9）成年人患有RVO，其中250万（CI, 1.9-3.1）患有CRVO， 1390万（CI, 11.5-16.4）患有BRVO。研究的局限性包括在识别研究参与者和RVO数据的获取和分级方面的不统一采样框架。我们的研究提供了RVO患病率的汇总数据，并表明大约有1600万人可能患有这种疾病。需要对这种威胁视力的眼病的预防和治疗策略进行研究。
To summarize the prevalence of retinal vein occlusion (RVO) from studies in the United States, Europe, Asia, and Australia. Pooled analysis using individual population-based data. Individual participant data from population-based studies around the world that had ascertained RVO from fundus photographs. Each study provided data on branch RVO and central RVO by age, sex, and ethnicity. Prevalence rates were directly age and sex standardized to the 2008 world population aged 30 years and older. Estimates were calculated by study and, after pooling, by ethnicity. Summary estimates included studies in which RVO was assessed from fundus photographs on ≥2 fields of both eyes. Any RVO, CRVO, or BRVO. The combined pooled data contained 68,751 individuals from 15 studies, with participants’ ages ranging from 30 to 101 years. In analyses of 11 studies that assessed ≥2 fundus fields of both eyes (n=49,869), the age- and sex-standardized prevalence was 5.20 per 1000 (confidence interval [CI], 4.40–5.99) for any RVO, 4.42 per 1000 (CI, 3.65–5.19) for BRVO, and 0.80 per 1000 (CI, 0.61–0.99) for CRVO. Prevalence varied by race/ethnicity and increased with age, but did not differ by gender. The age- and sex-standardized prevalence of any RVO was 3.7 per 1000 (CI, 2.8–4.6) in whites (5 studies), 3.9 per 1000 (CI, 1.8–6.0) in blacks (1 study), 5.7 per 1000 (CI, 4.5–6.8) in Asians (6 studies), and 6.9 per 1000 (CI, 5.7–8.3) in Hispanics (3 studies). Prevalence for CRVO was lower than BRVO in all ethnic populations. On the basis of these data, an estimated 16.4 million (CI, 13.9–18.9) adults are affected by RVO, with 2.5 million (CI, 1.9–3.1) affected by CRVO and 13.9 million (CI, 11.5–16.4) affected by BRVO. Study limitations include non-uniform sampling frames in identifying study participants and in acquisition and grading of RVO data. Our study provides summary data on the prevalence of RVO and suggests that approximately 16 million people may have this condition. Research on preventive and treatment strategies for this sight-threatening eye disease is needed.
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影响因子：
13.7
作者：
Klein, R;Klein, BEK;Jacobs, DR
通讯作者：
Jacobs, DR
影响因子：
4.4
作者：
Cheung, Ning;Klein, Ronald;Wong, Tien Yin
通讯作者：
Wong, Tien Yin
影响因子：
13.7
作者：
Mohamed, Quresh;McIntosh, Rachel L.;Wong, Tien Yin
通讯作者：
Wong, Tien Yin
影响因子：
14.6
作者：
Leenen, Frans H. H.;Dumais, Jean;Fodor, George
通讯作者：
Fodor, George
影响因子：
--
作者：
van Leeuwen, R;Klaver, CCW;de Jong, PTVM
通讯作者：
de Jong, PTVM