Differential responses of the mosquito Aedes albopictus from the Indian Ocean region to two chikungunya isolates.
Differential responses of the mosquito Aedes albopictus from the Indian Ocean region to two chikungunya isolates.
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DOI：
10.1186/1472-6785-10-8
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发表时间：
2010-03-12
期刊：
影响因子：
--
通讯作者：
Failloux AB
中科院分区：
文献类型：
--
作者：
Martin E;Moutailler S;Madec Y;Failloux AB
埃及伊蚊和白纹伊蚊都是基孔肯雅病毒（CHIKV）的载体。这两种伊蚊在印度洋地区共存，并参与了 2005-2006 年 CHIKV 的爆发。在留尼汪岛，病毒包膜中的单个突变被选择，导致伊蚊的高水平复制。白纹伊蚊，并且外部潜伏期短，因为感染后两天即可在唾液中发现病毒。一个重要的问题是，这种变异是否与影响蚊子某些生活史特征（例如生存和繁殖）的不利影响有关。我们使用三种伊蚊菌株进行了实验感染。埃及伊蚊马约特岛和伊伊。白纹伊蚊（马约特岛和留尼汪岛）和两种 CHIKV 毒株（E1-226A 和 E1-226V）。艾。马约特伊蚊对这两种病毒株同样敏感，而伊蚊。白纹伊蚊马约特岛和伊蚊。白纹伊留尼汪岛对 CHIKV E1-226V 比对 E1-226A 更敏感。在通过检查蚊子存活和繁殖来测量生活史特征方面，我们发现：（1）蚊子种类对两种病毒的反应之间观察到差异，（2）CHIKV感染仅显着影响伊蚊的一些生活史特征。白纹伊蚊 Reunion 而非其他两种蚊株，并且 (3) CHIKV 缩短了伊蚊的寿命。白纹伊蚊团聚并缩短了产卵前的时间。我们证明了 CHIKV 只会降低 Ae 的存活率。来自留尼汪岛的白纹伊蚊。通过在死亡前产卵，伊蚊进行繁殖。留尼汪岛的白纹伊蚊没有减少，因为表征产卵和孵化的其他参数没有受到影响。
Aedes aegypti and Aedes albopictus are both vectors of chikungunya virus (CHIKV). The two Aedes species co-exist in the Indian Ocean region and were involved in the 2005-2006 CHIKV outbreaks. In the Reunion Island, a single mutation in the viral envelope has been selected that leads to high levels of replication in Ae. albopictus, and a short extrinsic incubation period as the virus could be found in saliva as early as two days after infection. An important question is whether this variant is associated with adverse effects impacting some mosquito life-history traits such as survival and reproduction. We performed experimental infections using three mosquito strains of Ae. aegypti Mayotte and Ae. albopictus (Mayotte and Reunion), and two CHIKV strains (E1-226A and E1-226V). Ae. aegypti Mayotte were similarly susceptible to both viral strains, whereas Ae. albopictus Mayotte and Ae. albopictus Reunion were more susceptible to CHIKV E1-226V than to E1-226A. In terms of life-history traits measured by examining mosquito survival and reproduction, we found that: (1) differences were observed between responses of mosquito species to the two viruses, (2) CHIKV infection only affected significantly some life-history traits of Ae. albopictus Reunion and not of the other two mosquito strains, and (3) CHIKV reduced the lifespan of Ae. albopictus Reunion and shortened the time before egg laying. We demonstrated that CHIKV only reduces the survival of Ae. albopictus from the Reunion Island. By laying eggs just before death, reproduction of Ae. albopictus from the Reunion Island is not reduced since other parameters characterizing oviposition and hatching were not affected.
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影响因子：
2.7
作者：
Juliano, SA;Lounibos, LP;O'Meara, GF
通讯作者：
O'Meara, GF
影响因子：
2.1
作者：
Delatte, H.;Dehecq, J. S.;Fontenille, D.
通讯作者：
Fontenille, D.
DOI：
10.4269/ajtmh.1977.26.533
发表时间：
1977-01-01
影响因子：
3.3
作者：
KUBERSKI, TT;ROSEN, L
通讯作者：
ROSEN, L
DOI：
10.1016/j.trstmh.2004.03.013
发表时间：
2005-02-01
影响因子：
2.2
作者：
Laras, K;Sukri, NC;Corwin, AL
通讯作者：
Corwin, AL
影响因子：
2.1
作者：
GRIMSTAD, PR;ROSS, QE;CRAIG, GB
通讯作者：
CRAIG, GB