Prevalence and Factors Associated with Behavioural Problems in 5-year-old Children Born with Cleft Lip and/or Palate from the Cleft Collective
Prevalence and Factors Associated with Behavioural Problems in 5-year-old Children Born with Cleft Lip and/or Palate from the Cleft Collective
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唇裂和/或腭裂 5 岁儿童的患病率和行为问题相关因素
DOI：
10.1101/2021.08.04.21261594
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发表时间：
2021
期刊：
影响因子：
--
通讯作者：
Berman S
中科院分区：
文献类型：
--
作者：
Berman S
ObjectivesTo determine the UK prevalence of behavioral problems in 5-year old children born with isolated or syndromic cleft lip and/or palate（CL/P）compared to the general population. DesignObservatory study using questionnaire data from the Cleft Collective 5-Year-Old Cohort study and three general population samples.主要结果测量优势和困难问卷（SDQ）儿童（年龄：4.9-6.8岁）的母亲出生CL/P（n= 325）。SDQ评分的英国一般人群队列为：Millennium队列研究（MCS）（n= 12 511），国家统计局（ONS）规范性学龄SDQ数据（n= 5855）和雅芳家长和儿童纵向研究（ALSPAC）结果根据母亲的报告，14.2%的CL/P患儿的行为问题高于临床临界值，这比一般人群样本更有可能：MCS为7.5%（OR = 2.05 [1.49-2.82]，P< 0.001），ONS为9.8%（OR = 1.52 [1.10-2.09]，P= 0.008），ALSPAC为6.6%（OR = 2.34 [1.70-3.24]，P< 0.001）。在集体分裂的儿童有较高的几率多动症，情绪和同伴问题，和亲社会行为较少。产妇压力、产妇健康相关生活质量和家庭功能较低、接受政府收入支持和产妇吸烟显示出相关性的证据（OR范围：4.41-10.13）有行为问题，沿着母亲关系状况、年龄较小和受教育程度较低（OR范围：2.34-3.73）。结论研究结果表明，与一般人群相比，患有CL/P的儿童的行为问题水平较高，并且与一般人群相似的几个相关母亲因素。
ObjectivesTo determine the UK prevalence of behavioral problems in 5-year-old children born with isolated or syndromic cleft lip and/or palate (CL/P) compared to the general population and identify potentially associated factors.DesignObservational study using questionnaire data from the Cleft Collective 5-Year-Old Cohort study and three general population samples.Main Outcome MeasureThe Strengths and Difficulties Questionnaire (SDQ).ParticipantsMothers of children (age: 4.9-6.8 years) born with CL/P (n= 325). UK general population cohorts for SDQ scores were: Millennium Cohort Study (MCS) (n= 12 511), Office of National Statistics (ONS) normative school-age SDQ data (n= 5855), and Avon Longitudinal Study of Parents and Children (ALSPAC) (n= 9386).ResultsBy maternal report, 14.2% of children born with CL/P were above clinical cut-off for behavioral problems, which was more likely than in general population samples: 7.5% of MCS (OR = 2.05 [1.49-2.82],P< 0.001), 9.8% of ONS (OR = 1.52 [1.10-2.09],P= 0.008), and 6.6% of ALSPAC (OR = 2.34 [1.70-3.24],P< 0.001). Children in the Cleft Collective had higher odds for hyperactivity, emotional and peer problems, and less prosocial behaviors. Maternal stress, lower maternal health-related quality of life and family functioning, receiving government income support, and maternal smoking showed evidence of association (OR range: 4.41-10.13) with behavioral problems, along with maternal relationship status, younger age, and lower education (OR range: 2.34-3.73).ConclusionsFindings suggest elevated levels of behavioral problems in children born with CL/P compared to the general population with several associated maternal factors similar to the general population.
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影响因子：
5.2
作者：
Fitzsimons KJ;Copley LP;Setakis E;Charman SC;Deacon SA;Dearden L;van der Meulen JH
通讯作者：
van der Meulen JH
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DOI：
--
发表时间：
1992
期刊：
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作者：
J. Noar
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J. Noar
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DOI：
--
发表时间：
2015
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作者：
P. Thamilselvan;M. Kumar;J. Murthy;M. Sharma;N. Kumar
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追踪童年时期的情绪和行为变化：力量和困难问卷是否在不同时间测量相同的结构？
影响因子：
1.7
作者：
E. Sosu;P. Schmidt
通讯作者：
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DOI：
10.1177/1055665619862457
发表时间：
2020-01-01
期刊：
CLEFT PALATE-CRANIOFACIAL JOURNAL
影响因子：
--
作者：
Stock, Nicola Marie;Costa, Bruna;Rumsey, Nichola
通讯作者：
Rumsey, Nichola