Panzea: a database and resource for molecular and functional diversity in the maize genome.
Panzea: a database and resource for molecular and functional diversity in the maize genome.
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DOI：
10.1093/nar/gkj011
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发表时间：
2006-01-01
影响因子：
14.9
通讯作者：
Ware D
中科院分区：
文献类型：
--
作者：
Zhao W;Canaran P;Jurkuta R;Fulton T;Glaubitz J;Buckler E;Doebley J;Gaut B;Goodman M;Holland J;Kresovich S;McMullen M;Stein L;Ware D
作为社区资源，Panzea () 是玉米基因组分子和功能多样性项目的生物信息学部门。玉米是遗传研究的经典模型，是一种重要的作物物种，也是已知最多样化的作物物种。平均而言，两个随机选择的玉米品系每~100 bp就有一个单核苷酸多态性；这种差异大致相当于人类和黑猩猩之间的差异。这种特殊的基因型多样性是玉米需要在广泛的环境中种植的表型多样性的基础。玉米基因组项目的分子和功能多样性旨在了解选择如何塑造玉米的分子多样性，然后将分子多样性与功能表型变异联系起来。该项目将筛选 4000 个基因座以进行选择，并创建广泛的玉米和玉米-类蜀黍绘图群体。这些群体将被进行基因分型和表型分析，从而能够对性状进行高倍率和高分辨率的分析，并将分子多样性与功能变异联系起来。 Panzea 通过用户友好的基于网络的数据库搜索和数据检索/可视化工具以及与玉米多样性相关的各种信息和服务，提供对该项目产生的基因型、表型和多态性数据的访问。
Serving as a community resource, Panzea () is the bioinformatics arm of the Molecular and Functional Diversity in the Maize Genome project. Maize, a classical model for genetic studies, is an important crop species and also the most diverse crop species known. On average, two randomly chosen maize lines have one single-nucleotide polymorphism every ∼100 bp; this divergence is roughly equivalent to the differences between humans and chimpanzees. This exceptional genotypic diversity underlies the phenotypic diversity maize needs to be cultivated in a wide range of environments. The Molecular and Functional Diversity in the Maize Genome project aims to understand how selection has shaped molecular diversity in maize and then relate molecular diversity to functional phenotypic variation. The project will screen 4000 loci for the signature of selection and create a wide range of maize and maize–teosinte mapping populations. These populations will be genotyped and phenotyped, permitting high-power and high-resolution dissection of the traits and relating the molecular diversity to functional variation. Panzea provides access to the genotype, phenotype and polymorphism data produced by the project through user-friendly web-based database searches and data retrieval/visualization tools, as well as a wide variety of information and services related to maize diversity.
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影响因子：
14.9
作者：
Lawrence, CJ;Dong, OF;Brendel, V
通讯作者：
Brendel, V
DOI：
10.1073/pnas.052125199
发表时间：
2002-04-30
影响因子：
11.1
作者：
Matsuoka, Y;Vigouroux, Y;Doebley, J
通讯作者：
Doebley, J
影响因子：
14.9
作者：
Hulo, N;Sigrist, CJA;Bairoch, A
通讯作者：
Bairoch, A
影响因子：
14.9
作者：
Finn RD;Mistry J;Tate J;Coggill P;Heger A;Pollington JE;Gavin OL;Gunasekaran P;Ceric G;Forslund K;Holm L;Sonnhammer EL;Eddy SR;Bateman A
通讯作者：
Bateman A
影响因子：
7.4
作者：
Coe, E;Cone, K;Wing, R
通讯作者：
Wing, R