The impact of chronic rhinosinusitis on long-term survival in lung transplantation recipients

The impact of chronic rhinosinusitis on long-term survival in lung transplantation recipients
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慢性鼻窦炎对肺移植受者长期生存的影响

DOI:
10.1080/00016489.2016.1247497
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发表时间:
2017
影响因子:
1.4
通讯作者:
Nishizaki K.
Nishizaki K.
中科院分区:
医学4区
文献类型:
--
作者:
Kariya S;Okano M;Oto T;Higaki T;Haruna T;Noda Y;Nishizaki K.

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结论:根据2012年欧洲鼻窦炎和鼻息肉立场文件诊断的慢性鼻窦炎,而不是仅通过计算机断层扫描诊断,是影响肺移植患者长期生存的预后因素之一。鼻窦内镜手术可能在肺移植受者慢性鼻窦炎的治疗中发挥有益作用。目的:探讨鼻窦感染对肺移植后生存的影响。方法:本研究纳入肺移植受者。在肺移植之前和之后进行计算机断层扫描。采用Lund-Mackay评分系统评估慢性鼻窦炎的严重程度。采用Kaplan-Meier法计算生存率。结果:148例患者因不同适应症接受肺移植。 18.9%(28/148)的肺移植受者发现慢性鼻窦炎。在28名慢性鼻窦炎患者中,7名患者因持续鼻后滴漏而接受了鼻内窥镜手术。与没有慢性鼻窦炎的患者相比,未接受鼻内窥镜手术的慢性鼻窦炎患者(n=≥21)的存活率显着较低。计算机断层扫描显示有鼻旁窦异常 (n=≥50) 和无鼻旁窦异常 (n=≥98) 的受者之间的生存率没有统计学上的显着差异。
Conclusions:Chronic rhinosinusitis diagnosed according to the European Position Paper on Rhinosinusitis and Nasal Polyps 2012, not by computed tomography alone, is one of the prognostic factors affecting long-term survival in patients with lung transplantation. Endoscopic sinus surgery might play a beneficial role in the management of lung transplantation recipients with chronic rhinosinusitis.Objective:To show the effect of paranasal sinus infection on post-lung transplantation survival.Method:Lung transplantation recipients were included in this study. Computed tomography was performed before and after lung transplantation. The severity of chronic rhinosinusitis was evaluated by Lund–Mackay scoring system. The survival rate was calculated by the Kaplan–Meier method.Results:One hundred and forty-eight patients received lung transplantation for various indications. Chronic rhinosinusitis was found in 18.9% (28/148) of the lung transplantation recipients. Of 28 patients with chronic rhinosinusitis, seven patients underwent endoscopic sinus surgery due to persistent post-nasal drip. The recipients with chronic rhinosinusitis who did not receive endoscopic sinus surgery (n= 21) showed a significantly lower survival rate as compared to the patients without chronic rhinosinusitis. There was no statistically significant difference in the survival rate between the recipients with (n= 50) and without (n= 98) paranasal sinus abnormality on computed tomography.
DOI: 10.2500/ajr.2008.22.3146
发表时间: 2008-03-01
期刊: AMERICAN JOURNAL OF RHINOLOGY
影响因子: --
作者:
Leung, Man-Kit;Rachakonda, Leelanand;Hwang, Peter H.
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发表时间: 2013-12-01
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发表时间: 2013-01-01
影响因子: 2.6
作者:
Vital, Domenic;Hofer, Markus;Holzmann, David
通讯作者: Holzmann, David
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DOI: --
发表时间: 1997
期刊: Thorax
影响因子: 10
作者:
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DOI: --
发表时间: 2012
期刊: Acta Otorrinolaringológica Española
影响因子: --
作者:
Catalina Gutiérrez;G. Ribalta;I. Largo
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