Degeneration of the intervertebral disc.

Degeneration of the intervertebral disc.
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DOI:
10.1186/ar629
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发表时间:
2003
影响因子:
4.9
通讯作者:
Roberts S
Roberts S
中科院分区:
医学2区
文献类型:
--
作者:
Urban JP;Roberts S

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椎间盘是一种软骨结构,在生物化学方面类似于关节软骨,但在形态学上明显不同。它比身体中的任何其他结缔组织更早地显示出退行性和老化变化。它被认为是重要的临床,因为有一个协会的椎间盘退变与背痛。目前的治疗主要是保守的,或不太常见的手术;在许多情况下,没有明确的诊断和治疗被认为是不够的。新的发展,如遗传和生物学方法,可能会在未来提供更好的诊断和治疗。
The intervertebral disc is a cartilaginous structure that resembles articular cartilage in its biochemistry, but morphologically it is clearly different. It shows degenerative and ageing changes earlier than does any other connective tissue in the body. It is believed to be important clinically because there is an association of disc degeneration with back pain. Current treatments are predominantly conservative or, less commonly, surgical; in many cases there is no clear diagnosis and therapy is considered inadequate. New developments, such as genetic and biological approaches, may allow better diagnosis and treatments in the future.
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发表时间: 2002-01-15
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