Challenges in the Evaluation of Interventions to Improve Engagement Along the HIV Care Continuum in the United States: A Systematic Review.
Challenges in the Evaluation of Interventions to Improve Engagement Along the HIV Care Continuum in the United States: A Systematic Review.
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DOI：
10.1007/s10461-017-1687-8
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发表时间：
2017-07
影响因子：
4.4
通讯作者：
Shah M
中科院分区：
文献类型：
--
作者：
Risher KA;Kapoor S;Daramola AM;Paz-Bailey G;Skarbinski J;Doyle K;Shearer K;Dowdy D;Rosenberg E;Sullivan P;Shah M
在美国，艾滋病毒护理连续体系中的脱离程度很高。我们试图表征研究研究和干预措施的异质性，以改善确诊的艾滋病毒感染者的护理参与度。我们对2007年至2015年年中发表的干预措施进行了系统的文献搜索，以改善美国艾滋病毒与护理、护理保留、重新参与护理和坚持抗逆转录病毒治疗(ART)的联系。在纳入的研究中，研究设计和结果允许不同。我们将干预措施按类别、目标人群以及结果是否显著改善进行分组。我们确定了152项研究，7项(5%)关联研究，33项(22%)保留研究，4项(3%)重新参与研究，117项(77%)依从性研究。“关联”研究使用了11种不同的结果定义，而“保留”研究使用了39种，在效果测量方面几乎没有一致性。大多数研究(59%)报告了显著改善的结果，但这一比例和相应的影响大小在不同的研究类别中有很大差异。这篇综述突出了缺乏对联系和重新参与干预措施的评估；结果的概括性有限；以及干预类型、结果定义和效果衡量方面的显著异质性。为了在抗击美国的艾滋病毒流行方面取得进展，必须改进护理连续研究，并以综合、全面的框架为基准。
In the United States (US), there are high levels of disengagement along the HIV care continuum. We sought to characterize the heterogeneity in research studies and interventions to improve care engagement among people living with diagnosed HIV infection. We performed a systematic literature search for interventions to improve HIV linkage to care, retention in care, reengagement in care and adherence to antiretroviral therapy (ART) in the US published from 2007-mid 2015. Study designs and outcomes were allowed to vary in included studies. We grouped interventions into categories, target populations, and whether results were significantly improved. We identified 152 studies, 7 (5%) linkage studies, 33 (22%) retention studies, 4 (3%) reengagement studies, and 117 (77%) adherence studies. ‘Linkage’ studies utilized 11 different outcome definitions, while ‘retention’ studies utilized 39, with very little consistency in effect measurements. The majority (59%) of studies reported significantly improved outcomes, but this proportion and corresponding effect sizes varied substantially across study categories. This review highlights a paucity of assessments of linkage and reengagement interventions; limited generalizability of results; and substantial heterogeneity in intervention types, outcome definitions, and effect measures. In order to make strides against the HIV epidemic in the US, care continuum research must be improved and benchmarked against an integrated, comprehensive framework.
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影响因子：
4.9
作者：
Bradford, Judith B.;Coleman, Sharon;Cunningham, William
通讯作者：
Cunningham, William
影响因子：
4.4
作者：
Belzer, Marvin E.;Naar-King, Sylvie;Olson, Johanna;Sarr, Moussa;Thornton, Sarah;Kahana, Shoshana Y.;Gaur, Aditya H.;Clark, Leslie F.
通讯作者：
Clark, Leslie F.
影响因子：
4.4
作者：
Charania MR;Marshall KJ;Lyles CM;Crepaz N;Kay LS;Koenig LJ;Weidle PJ;Purcell DW;HIV/AIDS Prevention Research Synthesis (PRS) Team
通讯作者：
HIV/AIDS Prevention Research Synthesis (PRS) Team
DOI：
10.1521/aeap.2012.24.1.1
发表时间：
2012-02
期刊：
AIDS education and prevention : official publication of the International Society for AIDS Education
影响因子：
--
作者：
Bogart LM;Wagner GJ;Mutchler MG;Risley B;McDavitt BW;McKay T;Klein DJ
通讯作者：
Klein DJ
影响因子：
2
作者：
Cunningham CO;Sohler NL;Cooperman NA;Berg KM;Litwin AH;Arnsten JH
通讯作者：
Arnsten JH