Highly parallel fabrication of nanopatterned surfaces with nanoscale orthogonal biofunctionalization imprint lithography
Highly parallel fabrication of nanopatterned surfaces with nanoscale orthogonal biofunctionalization imprint lithography
复制标题
利用纳米级正交生物功能化压印光刻高度并行制造纳米图案表面
DOI:
10.1088/0957-4484/18/13/135101
复制
发表时间:
2007
期刊:
影响因子:
3.5
通讯作者:
W. Frey
中科院分区:
文献类型:
--
作者:
Harold E Gaubert;W. Frey
Large areas of nanopatterns of specific chemical functionality are needed for biological experiments and biotechnological applications. We present nanoscale orthogonal biofunctionalization imprint lithography (NOBIL), a parallel top-down imprinting and lift-off technique based on step-and-flash imprint lithography (SFIL) that is able to create centimetre-scale areas of nanopatterns of two biochemical functionalities. A photoresist precursor is polymerized with a template in place, and the thin resist layer is etched to create an undercut for lift-off. Gold nano-areas on a silicon dioxide background are then independently functionalized using self-assembly that translates the nanopattern into a cell-adhesive/cell-rejective functionality pattern. We demonstrate the technique by creating fibronectin areas down to a pattern size of 60 nm against a polyethylene glycol (PEG) background, and show initial results of cells stably seeded over an array of 1 mm2 areas of controlled size and pitch.
影响因子:
56.9
作者:
Chen, CS;Mrksich, M;Ingber, DE
通讯作者:
Ingber, DE
影响因子:
4
作者:
Koo,LilyY;Irvine,DarrellJ;Mayes,AnneM;Lauffenburger,DouglasA;Griffith,LindaG
通讯作者:
Griffith,LindaG
DOI:
--
发表时间:
2004
影响因子:
11.1
作者:
J. Tegenfeldt;C. Prinz;H. Cao;S. Chou;W. Reisner;R. Riehn;Yan Mei Wang;E. Cox;J. Sturm;
通讯作者:
J. Tegenfeldt;C. Prinz;H. Cao;S. Chou;W. Reisner;R. Riehn;Yan Mei Wang;E. Cox;J. Sturm;