A retrospective study on association between obesity and cardiovascular risk diseases with aging in Chinese adults.
A retrospective study on association between obesity and cardiovascular risk diseases with aging in Chinese adults.
复制标题
中国成年人肥胖和心血管危险疾病与衰老关系的回顾性研究。
DOI：
10.1038/s41598-018-24161-0
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发表时间：
2018-04-11
影响因子：
4.6
通讯作者：
Bi Y
中科院分区：
文献类型：
--
作者：
Sun J;Zhou W;Gu T;Zhu D;Bi Y
本研究旨在调查中国城市成年人群中不同性别和年龄组的超重和肥胖患病率及其与心血管疾病的关系。对南京市 384,061 名 20 岁及以上中国成年人进行回顾性分析。男性超重和肥胖年龄标准化患病率分别为42.8%和13.2%，女性分别为23.9%和6.6%。 2008年至2016年，超重和肥胖患病率呈逐渐上升趋势，尤其是20~39岁人群。超重和肥胖与血脂异常、糖尿病、高血压和高尿酸血症的风险增加显着相关。年龄削弱了两性的这种关系，这种关系在 20~39 岁的个体中激增。对于20~39岁的男性和女性，肥胖的OR（95% CI）达到4.23（4.01-4.47）和血脂异常5.29（4.63-6.04），糖尿病为3.70（2.97-4.60）和6.38（3.86-10.55），糖尿病为6.19高血压分别为 (5.76–6.64) 和 9.36 (7.86–11.13)，高尿酸血症分别为 3.66 (3.45–3.88) 和 6.65 (5.70–7.74)。超重和肥胖流行趋势呈上升趋势，是中国成年人特别是20~39岁人群心血管危险疾病的危险因素。
This study aimed to investigate the prevalence of overweight and obesity and its relationship with cardiovascular risk diseases among different sex and age groups in an urban Chinese adult population. A retrospective analysis was performed on 384,061 Chinese adults aged 20 years and older in Nanjing. The age-standardized prevalence of overweight and obesity was 42.8% and 13.2% in men and 23.9% and 6.6% in women. A gradually increasing trend was observed in the prevalence of overweight and obesity from 2008 to 2016, especially in individuals aged 20~39 years. Overweight and obesity were significantly associated with increased risks of dyslipidemia, diabetes mellitus, hypertension, and hyperuricemia. Age weakened such relationship for both genders, which spiked in individuals aged 20~39 years. For men and women aged 20~39 years, the OR (95% CI) of obesity reached 4.23 (4.01–4.47) and 5.29 (4.63–6.04) for dyslipidemia, 3.70 (2.97–4.60) and 6.38 (3.86–10.55) for diabetes mellitus, 6.19 (5.76–6.64) and 9.36 (7.86–11.13) for hypertension, and 3.66 (3.45–3.88) and 6.65 (5.70–7.74) for hyperuricemia, respectively. The increasing trend in the epidemic of overweight and obesity is a risk factor for cardiovascular risk diseases in Chinese adults, especially in individuals aged 20~39 years.
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影响因子：
5.1
作者：
Hsieh, SD;Muto, T
通讯作者：
Muto, T
影响因子：
6.9
作者：
Reynolds, Kristi;Gu, Dongfeng;Grp, InterASIA Collaborative
通讯作者：
Grp, InterASIA Collaborative
DOI：
10.1093/gerona/glt026
发表时间：
2014-01-01
影响因子：
5.1
作者：
Canning, Karissa L.;Brown, Ruth E.;Kuk, Jennifer L.
通讯作者：
Kuk, Jennifer L.
影响因子：
6.9
作者：
Cameron, Adrian J.;Boyko, Edward J.;Shaw, Jonathan E.
通讯作者：
Shaw, Jonathan E.
影响因子：
8.9
作者：
Chen, C. M.
通讯作者：
Chen, C. M.