100 years of Drosophila research and its impact on vertebrate neuroscience: a history lesson for the future.

100 years of Drosophila research and its impact on vertebrate neuroscience: a history lesson for the future.
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DOI:
10.1038/nrn2839
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发表时间:
2010-07
影响因子:
34.7
通讯作者:
Tsuda, Hiroshi
Tsuda, Hiroshi
中科院分区:
医学1区
文献类型:
--
作者:
Bellen, Hugo J.;Tong, Chao;Tsuda, Hiroshi

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果蝇的发现极大地促进了我们对神经科学的理解。使用空前丰富的工具,其中许多工具起源于1910年至1960年之间,使神经系统发育和功能方面的里程碑式发现成为可能。这些发现引发并指导了脊椎动物神经科学的许多研究工作。100年后,果蝇仍然是许多神经科学家的选择模型系统。强大的研究工具的组合使用将确保这种模式生物将继续导致影响脊椎动物神经科学的关键发现。
Discoveries in fruit flies have greatly contributed to our understanding of neuroscience. The use of an unparalleled wealth of tools, many of which originated between 1910–1960, has enabled milestone discoveries in nervous system development and function. Such findings have triggered and guided many research efforts in vertebrate neuroscience. After 100 years, fruit flies continue to be the choice model system for many neuroscientists. The combinational use of powerful research tools will ensure that this model organism will continue to lead to key discoveries that will impact vertebrate neuroscience.
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