Heightened biological stress response during exposure to a trauma film predicts an increase in intrusive memories.
Heightened biological stress response during exposure to a trauma film predicts an increase in intrusive memories.
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观看创伤影片期间生物应激反应的增强预示着侵入性记忆的增加
DOI：
10.1037/abn0000440
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发表时间：
2019
影响因子：
4.6
通讯作者：
Roepke
中科院分区：
文献类型：
--
作者：
Schultebraucks;Rombold-Bruehl;Wingenfeld;Hellmann-Regen;Roepke
一些人在经历了创伤事件后会出现创伤后应激障碍(PTSD)的症状，而另一些人则没有。侵袭性记忆是创伤后应激障碍的主要症状，更好地理解侵扰性记忆的编码和巩固可能会对创伤反应的差异产生重要的见解。本研究的主要目的是探讨在连续7天的模拟创伤编码和巩固过程中，心理社会应激诱导(Trier Social Stress Test)和主动控制(安慰剂版本)是否会导致各自的生物应激反应影响侵入式记忆的发展。我们假设，在7天的过程中，生物应激系统的激活会增加侵入性记忆的数量。这项单盲、随机、安慰剂对照研究检查了122名年轻健康女性。通过唾液皮质醇、唾液α-淀粉酶活性和心率变异性来衡量生物应激反应。使用广义线性混合模型分析生物应激反应的激活对自我报告的侵入式记忆数量的纵向影响。交叉验证正则化回归(最小绝对收缩和选择算子)被应用于数据驱动的特征选择，包括已知的生物和心理预测因子。特里尔社会压力测试的生物压力响应者报告说，创伤电影后的侵入性记忆明显更多，这证实了我们的假设。一项先验设计的事后测试表明，在生物应激反应的第一天和第二天，侵入性明显更多。最小绝对收缩和选择算子回归显示，创伤电影期间唾液皮质醇、唾液α-淀粉酶活性、心率变异性、主观评定的痛苦、恐惧和(在趋势水平上)分离是侵入性记忆的相关预测因素。年轻女性在经历类似创伤后的头几天，生物应激反应的增强与更具侵入性的记忆有关。(心理信息数据库记录(C)2022年APA，版权所有)
Some people develop symptoms of posttraumatic stress disorder (PTSD) after having experienced a traumatic event, whereas others do not. Intrusive memories are a cardinal symptom of PTSD and a better understanding of encoding and consolidation of intrusive memory may yield important insights on differences in the response to trauma. The primary aim of this study is to investigate whether psychosocial stress induction (Trier Social Stress Test) versus active control (placebo version) leading to respective biological stress responses during the encoding and consolidation of a film-elicited analogue trauma influences the development of intrusive memories over the course of 7 consecutive days. We hypothesized that the activation of the biological stress system increases the number of intrusive memories over the course of 7 days. This single-blind randomized placebo-controlled study examined 122 young healthy women. Biological stress response was measured by salivary cortisol, salivary α-amylase activity, and heart rate variability. Generalized linear mixed models were used to analyze longitudinal effects of activation of biological stress response on self-reported number of intrusive memories. Cross-validated regularized regression (least absolute shrinkage and selection operator) was applied for data-driven feature selection including known biological and psychological predictors. Corroborating our hypothesis, biological stress-responders to the Trier Social Stress Test reported significantly more intrusive memories after trauma film. A priori designed post hoc tests point at significantly more intrusions on Day 1 and 2 in biological stress responders. Least absolute shrinkage and selection operator regression revealed salivary cortisol, salivary α-amylase activity, heart rate variability, subjectively rated distress, fear, and (on trend level) dissociation during the trauma film as relevant predictors of intrusive memories. A heightened biological stress response in young women is associated with more intrusive memories the first days after experiencing a trauma analogue.(PsycInfo Database Record (c) 2022 APA, all rights reserved)
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