Prevalence of cavum septum pellucidum in schizophrenia studied with MRI

Prevalence of cavum septum pellucidum in schizophrenia studied with MRI
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MRI 研究精神分裂症中透明隔腔的患病率

DOI:
10.1016/s0920-9964(00)00110-9
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发表时间:
2001
影响因子:
4.5
通讯作者:
R. Tandon
R. Tandon
中科院分区:
医学2区
文献类型:
--
作者:
R. Rajarethinam;J. Miedler;J. Dequardo;Carolina Smet;J. Brunberg;R. Kirbat;R. Tandon

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目的了解精神分裂症患者中线发育异常透明隔腔(CSP)的患病率。方法对43例正常人和73例精神分裂症患者进行3 mm冠状位T1加权成像。图像被重采样成1 mm厚的切片,并根据其出现的层数来测量CSP。结果患者CSP的发生率显著高于对照组(Fisher‘s Exact检验0.042;单侧)。对照组中有18例(41.9%)和患者中有44例(60.3%)有CSP,46例对照组中有1例和73例患者中有3例有6层以上的大CSP。CSP的存在或大小与脑海马-杏仁复合体、尾状核、颞上回或脑室CSF的局部脑体积或体积无关。结论CSP的高发生率可能反映了精神分裂症的神经发育障碍。
ObjectiveTo study the prevalence of cavum septum pellucidum (CSP), a midline developmental anomaly, in patients with schizophrenia.MethodsThree-millimeter coronal T1 weighted MRI images of 43 normal controls and 73 patients with schizophrenia were examined. The images were resampled into 1-mm slices and CSP was measured by the number of slices in which it appeared.ResultsPatients had significantly higher incidence of CSP (Fisher's exact test 0.042; one-sided). Eighteen (41.9%) of the controls and 44 (60.3%) of patients had a CSP, and one of 46 controls and three of 73 patients had a large CSP of six slices or more. There was no relationship between the presence or size of CSP and regional brain volumes or volumes of hippocampus–amygdala complex, caudate, superior temporal gyrus or ventricular CSF.ConclusionHigher incidence of CSP may reflect a neurodevelopmental disturbance in schizophrenia.
精神分裂症和大透明隔腔患者的脑形态学模式。
DOI: 10.1176/jnp.8.2.147
发表时间: 1996
期刊: The Journal of neuropsychiatry and clinical neurosciences
影响因子: --
作者:
Nopoulos,P;Swayze,V;Andreasen,NC
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用于研究大脑结构和功能的图像处理:问题和程序。
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发表时间: 1992
期刊: The Journal of neuropsychiatry and clinical neurosciences
影响因子: --
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Andreasen,NC;Cohen,G;Harris,G;Cizadlo,T;Parkkinen,J;Rezai,K;Swayze2nd,VW
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发表时间: 1998-04-01
影响因子: 17.7
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Kwon, JS;Shenton, ME;McCarley, RW
通讯作者: McCarley, RW
DOI: --
发表时间: 1992
期刊: AJNR. American journal of neuroradiology
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Degreef,G;Lantos,G;Bogerts,B;Ashtari,M;Lieberman,J
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