Sex Disparities in COVID-19 Mortality Vary Across US Racial Groups.

Sex Disparities in COVID-19 Mortality Vary Across US Racial Groups.
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DOI:
10.1007/s11606-021-06699-4
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发表时间:
2021-06
影响因子:
5.7
通讯作者:
Shattuck-Heidorn H
Shattuck-Heidorn H
中科院分区:
医学2区
文献类型:
--
作者:
Rushovich T;Boulicault M;Chen JT;Danielsen AC;Tarrant A;Richardson SS;Shattuck-Heidorn H

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在美国,COVID-19结果的不平等在性别和种族方面有明确的记录:男性的死亡率高于女性,黑人的死亡率高于白色。然而,尚未探索的是性别和种族如何在COVID-19结果中相互作用。使用现有数据描述美国两个州种族和性别阶层内和种族与性别阶层之间的COVID-19死亡率,旨在了解COVID-19死亡的明显性别差异如何在种族之间变化。这项观察性研究使用了截至2020年9月21日的COVID-19死亡率数据,来自格鲁吉亚(GA)和密歇根州(MI)。我们计算了每个性别-种族-年龄层的年龄特异性比率,以及每个种族-性别层的年龄标准化比率。我们调查种族群体内的性别差异和性别群体内的种族差异,使用年龄标准化率比和率差。在种族群体中,男性的COVID-19死亡率高于女性。在所有种族性别组中,黑人男性的死亡率最高(MI:254.6,每10万人死亡,95% CI:241.1-268.2,GA:128.5,95% CI:121.0-135.9)。在MI中,黑人女性的COVID-19死亡率(147.1,95% CI:138.7-155.4)高于白色男性(39.1,95% CI:37.3-40.9)、白色女性(29.7,95% CI:28.3-31.0)和亚洲/太平洋岛民男性和女性。GA的COVID-19死亡率遵循相同模式。在MI中,黑人个体的男女死亡率比率为1.7(1.5-2.0),而白色个体的比率仅为1.3(1.2-1.5)。虽然总体而言,男性的COVID-19死亡率高于女性,但我们的研究结果表明,这种性别差异并不存在于种族群体中。这表明了单维报告和分析的局限性,并强调了种族和性别交叉影响COVID-19结果的方式。
Inequities in COVID-19 outcomes in the USA have been clearly documented for sex and race: men are dying at higher rates than women, and Black individuals are dying at higher rates than white individuals. Unexplored, however, is how sex and race interact in COVID-19 outcomes. Use available data to characterize COVID-19 mortality rates within and between race and sex strata in two US states, with the aim of understanding how apparent sex disparities in COVID-19 deaths vary across race. This observational study uses COVID-19 mortality data through September 21, 2020, from Georgia (GA) and Michigan (MI). We calculate age-specific rates for each sex-race-age stratum, and age-standardized rates for each race-sex stratum. We investigate the sex disparity within race groups and the race disparity within sex groups using age-standardized rate ratios, and rate differences. Within race groups, men have a higher COVID-19 mortality rate than women. Black men have the highest rate of all race-sex groups (in MI: 254.6, deaths per 100,000, 95% CI: 241.1–268.2, in GA:128.5, 95% CI: 121.0-135.9). In MI, the COVID-19 mortality rate for Black women (147.1, 95% CI: 138.7–155.4) is higher than the rate for white men (39.1, 95% CI: 37.3–40.9), white women (29.7, 95% CI: 28.3–31.0), and Asian/Pacific Islander men and women. COVID-19 mortality rates in GA followed the same pattern. In MI, the male:female mortality rate ratio among Black individuals is 1.7 (1.5–2.0) while the rate ratio among White individuals is only 1.3 (1.2–1.5). While overall, men have higher COVID-19 mortality rates than women, our findings show that this sex disparity does not hold across racial groups. This demonstrates the limitations of unidimensional reporting and analyses and highlights the ways that race and gender intersect to shape COVID-19 outcomes.
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