Programmable periodicity of quantum dot arrays with DNA origami nanotubes.

Programmable periodicity of quantum dot arrays with DNA origami nanotubes.
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DOI:
10.1021/nl101079u
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发表时间:
2010-09-08
期刊:
影响因子:
10.8
通讯作者:
Hughes WL
Hughes WL
中科院分区:
材料科学1区
文献类型:
--
作者:
Bui H;Onodera C;Kidwell C;Tan Y;Graugnard E;Kuang W;Lee J;Knowlton WB;Yurke B;Hughes WL

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为了制备具有可编程周期性的量子点阵列,开发了功能化的DNA折纸纳米管。选择的DNA钉合链被生物素标记以形成用于链霉亲和素缀合的量子点的周期性结合位点。周期为43和71 nm的阵列的成功形成证明了精确的、可编程的、大规模的纳米颗粒图案化;然而,也观察到阵列周期性的限制。AFM图像的统计分析显示空间位阻或位点桥接的证据,限制了最小的阵列周期。
To fabricate quantum dot arrays with programmable periodicity, functionalized DNA origami nanotubes were developed. Selected DNA staple strands were biotin-labeled to form periodic binding sites for streptavidin-conjugated quantum dots. Successful formation of arrays with periods of 43 and 71 nm demonstrates precise, programmable, large-scale nanoparticle patterning; however, limitations in array periodicity were also observed. Statistical analysis of AFM images revealed evidence for steric hindrance or site bridging that limited the minimum array periodicity.
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