The Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) mRNA Vaccine-Breakthrough Infection Phenotype Includes Significant Symptoms, Live Virus Shedding, and Viral Genetic Diversity.

The Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) mRNA Vaccine-Breakthrough Infection Phenotype Includes Significant Symptoms, Live Virus Shedding, and Viral Genetic Diversity.
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DOI:
10.1093/cid/ciab543
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发表时间:
2022-03-09
期刊:
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
影响因子:
--
通讯作者:
Burgess TH
Burgess TH
中科院分区:
其他
文献类型:
--
作者:
Pollett SD;Richard SA;Fries AC;Simons MP;Mende K;Lalani T;Lee T;Chi S;Mody R;Madar C;Ganesan A;Larson DT;Colombo CJ;Colombo R;Samuels EC;Broder CC;Laing ED;Smith DR;Tribble D;Agan BK;Burgess TH

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关于严重急性呼吸综合征冠状病毒2型“疫苗突破”感染(VBIs)知之甚少。在这里,我们的特点24 VBIs主要是年轻健康的人。虽然没有人需要住院治疗,但有一部分人出现了严重的症状,并脱落了高达4.13 × 103个空斑形成单位/mL的活病毒。  感染基因型包括关注变异株(VOC)和非VOC菌株。
Little is known about severe acute respiratory syndrome coronavirus 2 “vaccine-breakthrough” infections (VBIs). Here we characterize 24 VBIs in predominantly young healthy persons. While none required hospitalization, a proportion endorsed severe symptoms and shed live virus as high as 4.13 × 103 plaque-forming units/mL. Infecting genotypes included both variant-of-concern (VOC) and non-VOC strains.
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影响因子: 82.9
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