Potential endocrine correlation with exposure to domoic acid in Southern Right Whale (Eubalaena australis) at the Península Valdés breeding ground
Potential endocrine correlation with exposure to domoic acid in Southern Right Whale (Eubalaena australis) at the Península Valdés breeding ground
复制标题
瓦尔德斯半岛繁殖地的南露脊鲸(Eubalaena australis)与暴露于软骨藻酸的潜在内分泌相关性
DOI:
10.1007/s00442-021-05078-4
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发表时间:
2022
期刊:
影响因子:
2.7
通讯作者:
Buck, C. Loren
中科院分区:
文献类型:
--
作者:
D’Agostino, Valeria C.;Fernández Ajó, Alejandro;Degrati, Mariana;Krock, Bernd;Hunt, Kathleen E.;Uhart, Marcela M.;Buck, C. Loren
In waters off Península Valdés (PV), Argentina, southern right whales (SRW,Eubalaena australis) are occasionally exposed to domoic acid (DA), a neurotoxin produced by diatoms of the genusPseudo-nitzschia. Domoic acid toxicity in marine mammals can cause gastrointestinal and neurological clinical signs, alterations in hematologic and endocrine variables, and can be fatal in extreme cases. In this study, we validated an enzyme immunoassay to quantify fecal glucocorticoid metabolites (fGCm) in 16 SRW fecal samples from live and dead stranded whales in PV from 2013 to 2018 and assessed fGCm levels associated with DA exposure. Overall, fGCm levels were significantly lower in SRWs with detectable fecal DA (n= 3) as compared to SRWs with undetectable fecal DA levels (n= 13). The highest fecal DA was observed in a live lactating female, which had low fGCm compared to the other lactating females studied. The highest fGCm was observed in a lactating female with undetectable DA; interestingly, at the time of sample collection, this female was sighted with two calves, an extremely unusual occurrence in this species. Though the sample size of these exceptionally rare breeding-season fecal samples was unavoidably small, our study provides evidence of potential adrenal alterations in whales exposed to an environmental neurotoxin such as DA.
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DOI:
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发表时间:
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期刊:
影响因子:
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作者:
C. Gabriele;L. Taylor;K. Burek Huntington;C. Buck;K. Hunt;K. Lefebvre;C. Lockyer;Carley L. Lowe;J. Moran;A. Murphy;Matthew Rogers;S. Trumble;S. Raverty
通讯作者:
S. Raverty
影响因子:
64.8
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Scholin, CA;Gulland, F;Van Dolah, FM
通讯作者:
Van Dolah, FM
影响因子:
2.7
作者:
Wasser, SK;Hunt, KE;Monfort, SL
通讯作者:
Monfort, SL
影响因子:
1.3
作者:
Goldstein, Tracey;Zabka, Tanja S.;Gulland, Frances M. D.
通讯作者:
Gulland, Frances M. D.
DOI:
--
发表时间:
2015
期刊:
影响因子:
--
作者:
P. Best;S. Elwen;P. Palsbøll;M. Thornton;Evan Austin;Katja Vinding
通讯作者:
Katja Vinding