Motion correction for myocardial T1 mapping using image registration with synthetic image estimation.

Motion correction for myocardial T1 mapping using image registration with synthetic image estimation.
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DOI:
10.1002/mrm.23153
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发表时间:
2012-06
影响因子:
3.3
通讯作者:
Kellman, Peter
Kellman, Peter
中科院分区:
医学3区
文献类型:
--
作者:
Xue, Hui;Shah, Saurabh;Greiser, Andreas;Guetter, Christoph;Littmann, Arne;Jolly, Marie-Pierre;Arai, Andrew E.;Zuehlsdorff, Sven;Guehring, Jens;Kellman, Peter

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定量测定心肌T1松弛对诊断缺血性和非缺血性心肌病均有潜在价值。采用改进的Look-Locker反转恢复技术采集图像用于T1标测是临床可行的。然而,呼吸运动限制了它的适用性,降低了T1估计的准确性。由于图像对比度的巨大变化,尤其是对于在反转恢复的信号零点附近采集的图像和组织对比度很小的其他反转时间,获取的反转恢复图像的稳健配准尤其具有挑战性。本文提出了一种新的运动校正算法。该方法基于对呈现与采集图像相似的对比度变化的合成图像的估计。合成图像的估计被表示为一个变分能量最小化问题。在连续的患者数据队列上的验证表明,该策略可以执行稳健的非刚性配准,以对齐经历显著运动的反转恢复图像,并导致抑制T1图中的运动诱导伪影。
Quantification of myocardial T1 relaxation has potential value in the diagnosis of both ischemic and non-ischemic cardiomyopathies. Image acquisition using the Modified Look-Locker Inversion Recovery technique is clinically feasible for T1 mapping. However, respiratory motion limits its applicability and degrades the accuracy of T1 estimation. The robust registration of acquired inversion recovery images is particularly challenging due to the large changes in image contrast, especially for those images acquired near the signal null point of the inversion recovery and other inversion times for which there is little tissue contrast. In this paper, we propose a novel motion correction algorithm. This approach is based on estimating synthetic images presenting contrast changes similar to the acquired images. The estimation of synthetic images is formulated as a variational energy minimization problem. Validation on a consecutive patient data cohort shows that this strategy can perform robust non-rigid registration to align inversion recovery images experiencing significant motion and lead to suppression of motion induced artifacts in the T1 map.
DOI: 10.1186/1532-429x-13-16
发表时间: 2011-03-04
期刊: Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance
影响因子: --
作者:
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期刊: ECOLOGY
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作者:
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