Involvement of Mitochondrial Disorders in Septic Cardiomyopathy.

Involvement of Mitochondrial Disorders in Septic Cardiomyopathy.
复制标题

DOI:
10.1155/2017/4076348
复制
发表时间:
2017
影响因子:
--
通讯作者:
Preau S
Preau S
中科院分区:
生物学2区
文献类型:
--
作者:
Durand A;Duburcq T;Dekeyser T;Neviere R;Howsam M;Favory R;Preau S

文献摘要

参考文献

被引文献

相似文献

脓毒症定义为由宿主对感染的反应失调引起的危及生命的器官功能障碍。尽管开发了各种治疗策略,但它仍然是全球死亡的主要原因。心功能不全,也被称为脓毒性心肌病,是脓毒症的常见并发症,并与更差的临床结局相关。最近的研究增加了我们对线粒体功能障碍在脓毒性心肌病病理生理学中的作用的理解。这篇综述的目的是将这些证据作为一个连贯的整体,并强调未来的研究方向。
Sepsis is defined as a life-threatening organ dysfunction caused by a dysregulated host response to infection. It remains a leading cause of death worldwide, despite the development of various therapeutic strategies. Cardiac dysfunction, also referred to as septic cardiomyopathy, is a frequent and well-described complication of sepsis and associated with worse clinical outcomes. Recent research has increased our understanding of the role of mitochondrial dysfunction in the pathophysiology of septic cardiomyopathy. The purpose of this review is to present this evidence as a coherent whole and to highlight future research directions.
DOI: 10.1161/circresaha.116.303554
发表时间: 2015-01-02
影响因子: 20.1
作者:
Dorn GW 2nd;Kitsis RN
通讯作者: Kitsis RN
DOI: 10.1097/01.ccm.0000114827.93410.d8
发表时间: 2004-03-01
影响因子: 8.8
作者:
Charpentier, J;Luyt, CE;Chiche, JD
通讯作者: Chiche, JD
DOI: 10.1179/acb.2010.070
发表时间: 2010-09-01
影响因子: 1.6
作者:
De Kock, I.;Van Daele, C.;Poelaert, J.
通讯作者: Poelaert, J.
DOI: 10.12688/f1000research.10397.1
发表时间: 2017
期刊: F1000Research
影响因子: --
作者:
Boyapati RK;Tamborska A;Dorward DA;Ho GT
通讯作者: Ho GT
DOI: 10.1016/j.gene.2008.01.007
发表时间: 2008-03-31
期刊: GENE
影响因子: 3.5
作者:
Amo, Taku;Yadava, Nagendra;Oh, Richard;Nicholls, David G.;Brand, Martin D.
通讯作者: Brand, Martin D.