g:Profiler--a web server for functional interpretation of gene lists (2011 update).
g:Profiler--a web server for functional interpretation of gene lists (2011 update).
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G:Profiler- - 用于基因列表功能解释的Web服务器(2011年更新)。
DOI:
10.1093/nar/gkr378
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发表时间:
2011-07
影响因子:
14.9
通讯作者:
Vilo J
中科院分区:
文献类型:
--
作者:
Reimand J;Arak T;Vilo J
Functional interpretation of candidate gene lists is an essential task in modern biomedical research. Here, we present the 2011 update of g:Profiler (http://biit.cs.ut.ee/gprofiler/), a popular collection of web tools for functional analysis. g:GOSt and g:Cocoa combine comprehensive methods for interpreting gene lists, ordered lists and list collections in the context of biomedical ontologies, pathways, transcription factor and microRNA regulatory motifs and protein–protein interactions. Additional tools, namely the biomolecule ID mapping service (g:Convert), gene expression similarity searcher (g:Sorter) and gene homology searcher (g:Orth) provide numerous ways for further analysis and interpretation. In this update, we have implemented several features of interest to the community: (i) functional analysis of single nucleotide polymorphisms and other DNA polymorphisms is supported by chromosomal queries; (ii) network analysis identifies enriched protein–protein interaction modules in gene lists; (iii) functional analysis covers human disease genes; and (iv) improved statistics and filtering provide more concise results. g:Profiler is a regularly updated resource that is available for a wide range of species, including mammals, plants, fungi and insects.
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影响因子:
64.8
作者:
通讯作者:
--
影响因子:
12.3
作者:
Adler P;Kolde R;Kull M;Tkachenko A;Peterson H;Reimand J;Vilo J
通讯作者:
Vilo J
影响因子:
14.9
作者:
Khatri P;Voichita C;Kattan K;Ansari N;Khatri A;Georgescu C;Tarca AL;Draghici S
通讯作者:
Draghici S
影响因子:
7
作者:
Gennarino, Vincenzo Alessandro;Sardiello, Marco;Banfi, Sandro
通讯作者:
Banfi, Sandro
影响因子:
14.9
作者:
Griffiths-Jones, Sam;Saini, Harpreet Kaur;van Dongen, Stijn;Enright, Anton J.
通讯作者:
Enright, Anton J.