Multinuclear absolute magnetic resonance thermometry
Multinuclear absolute magnetic resonance thermometry
复制标题
多核绝对磁共振测温
DOI:
10.1038/s42005-019-0252-3
复制
发表时间:
2019
影响因子:
5.5
通讯作者:
Alon, Leeor
中科院分区:
文献类型:
--
作者:
Silletta, Emilia V.;Jerschow, Alexej;Madelin, Guillaume;Alon, Leeor
Non-invasive measurement of absolute temperature is important for proper characterization of various pathologies and for evaluation of thermal dose during interventional procedures. The proton (hydrogen nucleus) magnetic resonance (MR) frequency shift method can be used to map relative temperature changes. However, spatiotemporal variations in the main magnetic field and the lack of local internal frequency reference challenge the determination of absolute temperature. Here, we introduce a multinuclear method for absolute MR thermometry, based on the fact that the hydrogen and sodium nuclei exhibit a unique and distinct characteristic frequency dependence with temperature and with electrolyte concentration. A one-to-one mapping between the precession frequency difference of the two nuclei and absolute temperature is demonstrated. Proof-of-concept experiments were conducted in aqueous solutions with different NaCl concentrations, in agarose gel samples, and in freshly excised ex vivo mouse tissues. One-dimensional chemical shift imaging experiments also demonstrated excellent agreement with infrared measurements.
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影响因子:
3.3
作者:
Holbrook, Andrew B.;Santos, Juan M.;Kaye, Elena;Rieke, Viola;Pauly, Kim Butts
通讯作者:
Pauly, Kim Butts
影响因子:
4.4
作者:
J. Wertz;O. Jardetzky
通讯作者:
O. Jardetzky
DOI:
--
发表时间:
1968
期刊:
影响因子:
--
作者:
A. L. V. Geet
通讯作者:
A. L. V. Geet
DOI:
--
发表时间:
1968
期刊:
影响因子:
--
作者:
J. Hindman
通讯作者:
J. Hindman
DOI:
10.1016/j.ejmp.2009.11.006
发表时间:
2010-10-01
期刊:
PHYSICA MEDICA
影响因子:
--
作者:
Kickhefel, A.;Roland, Joerg;Schick, Fritz
通讯作者:
Schick, Fritz