Mechanisms of microRNA-mediated regulation of angiogenesis.
Mechanisms of microRNA-mediated regulation of angiogenesis.
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microRNA 介导的血管生成调节机制。
DOI:
10.2741/e191
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发表时间:
2010-06
期刊:
影响因子:
--
通讯作者:
中科院分区:
文献类型:
--
作者:
Stroke is the second most common cause of death and consumes about 2-4% of total health-care costs worldwide. Although most studies have focused on neuroprotection during the past decades, current therapeutic options are still very limited. Recently scientists have intensified their work on neurorestorative therapies, including angiogenesis, which allow a far greater time window for improving neurological recovery. MicroRNAs have emerged as crucial players, regulating almost every cellular process investigated to date, and evidence of their role in the context of angiogenesis and stroke has been rapidly accumulating. The goal of this review is to summarize the mechanisms of microRNA-mediated regulation of angiogenesis and the implications for a novel molecular approach to enhance neurological recovery after stroke.
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DOI:
10.1038/jcbfm.2008.157
发表时间:
2009-04
期刊:
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism
影响因子:
--
作者:
通讯作者:
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影响因子:
56.9
作者:
Asahara, T;Murohara, T;Isner, JM
通讯作者:
Isner, JM
DOI:
--
发表时间:
1999-04
期刊:
Laboratory investigation; a journal of technical methods and pathology
影响因子:
--
作者:
R. Issa;J. Krupiński;T. Bujny;Shant Kumar;J. Kałuża;Patricia Kumar
通讯作者:
R. Issa;J. Krupiński;T. Bujny;Shant Kumar;J. Kałuża;Patricia Kumar
影响因子:
3.5
作者:
Hutchison, Emmette R.;Okun, Eitan;Mattson, Mark P.
通讯作者:
Mattson, Mark P.