Prevention of recurrence of major depression among emerging adults by a group cognitive-behavioral/interpersonal intervention.
Prevention of recurrence of major depression among emerging adults by a group cognitive-behavioral/interpersonal intervention.
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DOI：
10.1016/j.jad.2012.08.036
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发表时间：
2013-05
影响因子：
6.6
通讯作者：
Craighead, W. Edward
中科院分区：
文献类型：
--
作者：
Sheets, Erin S.;Craighead, Linda Wilcoxon;Brosse, Alisha L.;Hauser, Monika;Madsen, Joshua W.;Craighead, W. Edward
青春期重性抑郁症（MDD）首次发作的最严重后遗症之一是复发概率的显著增加。本研究报告了一个综合的CBT/IPT计划，以小组形式提供，旨在降低新兴成年人的MDD复发率。参与者是89名年轻人，他们在进入研究时没有抑郁症，但在青春期经历过MDD。参与者被分配到CBT/IPT预防计划或仅评估控制条件，并在大学的前2年进行随访。与仅评估对照组相比，预防计划参与者的MDD复发风险降低了50%以上。干预还对那些完成大部分小组会议的学生的学习成绩产生了有益的影响。这项研究包括一个自我选择的样本，这些样本是意识到自己有抑郁症史的新兴成年人。由于样本量小，在足够把握度的试验中评价类似干预措施以确定这是否是一个可复制的发现将是重要的。51%的评估参与者在大学的前两年经历了MDD复发，这些发现支持了旨在预防年轻人MDD复发的计划的必要性。目前的计划，基于IPT和CBT原则，似乎降低了以前抑郁的新兴成年人的MDD复发率。
Among the most serious sequelae to an initial episode of Major Depressive Disorder (MDD) during adolescence is the significant increase in the probability of recurrence. This study reports on an integrated CBT/IPT program, provided in a group format, that was developed to decrease the rate of MDD recurrence in emerging adults. Participants were 89 young adults who were not depressed at study entry but had experienced MDD during adolescence. Participants were assigned to a CBT/IPT prevention program or to an assessment only control condition and were followed through the first 2 years of college. Risk for MDD recurrence was reduced more than 50% for the prevention program participants compared to assessment only controls. The intervention also conferred beneficial effects on academic performance for those students who completed the majority of the group sessions. The study included a self-selected sample of emerging adults who were aware of their history of depression. Due to the small sample size, it will be important to evaluate similar interventions in adequately-powered trials to determine if this is a replicable finding. With 51% of the assessment only participants experiencing a MDD recurrence during the first 2 years of college, these findings support the need for programs designed to prevent MDD recurrence in young adults. The current program, based on IPT and CBT principles, appears to reduce the rate of MDD recurrence among previously depressed emerging adults.
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