Clinical 3D Imaging of the Anterior Segment With Ultrasound Biomicroscopy.
Clinical 3D Imaging of the Anterior Segment With Ultrasound Biomicroscopy.
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超声生物显微镜下眼前节的临床3D成像。
DOI：
10.1167/tvst.10.3.11
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发表时间：
2021-03-01
影响因子：
3
通讯作者：
Örge FH
中科院分区：
文献类型：
--
作者：
Helms RW;Minhaz AT;Wilson DL;Örge FH
超声生物显微镜（UBM）是一种重要的眼科成像方式，因为它能够看到色素虹膜后面，并在眼睛的透明度受损时显示前房。我们创建了一个三维UBM（3D-UBM）系统，并获得了示例图像，以说明其潜力。将商用50 MHz二维UBM（2D-UBM）系统连接到精密平移台，并平移穿过眼睛以获取图像体积。载物台安装在手术显微镜上，可以安全、稳定地定位。图像处理步骤包括图像对齐、降噪和校准。3D可视化包括光轴对准、任意方向的多平面重新格式化以及具有优化传递函数的体绘制。对尸体和兔眼进行扫描。与2D-UBM不同，3D-UBM允许在3D解剖背景下可视化眼前节组织。正面视图和交互式切片机操作表明能够计划和评估治疗，包括透镜放置和施累姆氏管的微导管插管。交互式软件允许我们对组织结构进行精确测量（例如，虹膜角膜角、囊肿体积）。此外，睫状组织的独特测量值包括0.234 ± 0.093 mm 3的单个睫状突体积，表面积为3.02 ± 1.07 mm 2，以及67.87 mm 3的睫状肌体积。眼前节的3D-UBM成像可用于实现眼前节结构的独特可视化和量化。3D-UBM提供了眼睛中组织的信息3D成像，这些组织对光不可见，与传统的2D-UBM相比，可能为医生提供改进的诊断、治疗计划和治疗评估。
Ultrasound biomicroscopy (UBM) is an important ophthalmic imaging modality due to its ability to see behind pigmented iris and to visualize anterior chamber when the eye's transparency is compromised. We created a three-dimensional UBM (3D-UBM) system and acquired example images to illustrate its potential. A commercial 50-MHz two-dimensional UBM (2D-UBM) system was attached to a precision translation stage and translated across the eye to acquire an image volume. The stage was mounted on a surgical microscope, which enabled safe, stable positioning. Image processing steps included image alignment, noise reduction, and calibration. 3D visualization included alignment of the optic axis, multiplanar reformatting at arbitrary orientations, and volume rendering with optimized transfer functions. Scans were performed on cadaver and rabbit eyes. 3D-UBM allowed visualization of the anterior segment tissues within a 3D anatomical context, unlike 2D-UBM. En face views and interactive slicer operations suggested an ability to plan and assess treatments, including lens placement and microcatheter cannulation of Schlemm's canal. Interactive software allowed us to make accurate measurements of tissue structures (e.g., iridocorneal angles, cyst volumes). In addition, unique measurements of ciliary tissues included single ciliary process volumes of 0.234 ± 0.093 mm3 with surface areas of 3.02 ± 1.07 mm2 and ciliary muscle volume of 67.87 mm3. 3D-UBM imaging of the anterior segment can be used to enable unique visualization and quantification of anterior segment structures. 3D-UBM provides informative 3D imaging of tissues in the eye that are invisible to light to potentially provide physicians with improved diagnosis, treatment planning, and treatment assessment as compared to conventional 2D-UBM.
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急性和慢性原发性闭角（青光眼）对侧眼之间的差异：超声生物显微镜定量研究。
影响因子：
3.7
作者：
Li M;Chen Y;Chen X;Zhu W;Chen X;Wang X;Fang Y;Kong X;Dai Y;Chen J;Sun X
通讯作者：
Sun X
DOI：
10.1007/s004170100370
发表时间：
2001-12-01
影响因子：
2.7
作者：
Kirchhoff, A;Stachs, O;Guthoff, R
通讯作者：
Guthoff, R
影响因子：
2.9
作者：
Xiao, Han;Tan, Yuting;Wang, Jianping
通讯作者：
Wang, Jianping
影响因子：
13.7
作者：
Cusumano, A;Coleman, DJ;Lloyd, HO
通讯作者：
Lloyd, HO
影响因子：
4.1
作者：
Finger, PT;Khoobehi, A;Garcia, JPS
通讯作者：
Garcia, JPS