Self-recognition of one's own fall recruits the genuine bodily crisis-related brain activity.
Self-recognition of one's own fall recruits the genuine bodily crisis-related brain activity.
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DOI：
10.1371/journal.pone.0115303
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发表时间：
2014
期刊：
影响因子：
3.7
通讯作者：
Kikuchi Y
中科院分区：
文献类型：
--
作者：
Atomi T;Noriuchi M;Oba K;Atomi Y;Kikuchi Y
虽然两足行走是一种基本的进化适应，被认为对人类大脑的发育至关重要，但直立的身体总是离摔倒只有一两英寸。虽然自动检测自身身体不稳定性的神经机制是一个重要的考虑因素，但由于对参与者运动的限制，迄今为止很少有功能性神经成像研究。在这里，我们使用功能性磁共振成像来研究全身不稳定性背后的神经基质，基于自我识别范式，该范式使用由稳定和不稳定状态下描绘的自己和他人的全身组成的视频刺激。分析显示，在真正的不稳定的身体状态下，将被激活的区域有显着的活动：右顶叶岛前庭皮质，额下交界处，后丘脑和臂旁核。我们认为，这些右侧皮质和脑干区域介导前庭信息处理检测前庭异常，防御性运动反应，其中必要的运动反应自动准备/模拟，以保护自己的身体，和交感神经活动作为一种形式的报警响应在全身不稳定。
While bipedalism is a fundamental evolutionary adaptation thought to be essential for the development of the human brain, the erect body is always an inch or two away from falling. Although the neural mechanism for automatically detecting one's own body instability is an important consideration, there have thus far been few functional neuroimaging studies because of the restrictions placed on participants' movements. Here, we used functional magnetic resonance imaging to investigate the neural substrate underlying whole body instability, based on the self-recognition paradigm that uses video stimuli consisting of one's own and others' whole bodies depicted in stable and unstable states. Analyses revealed significant activity in the regions which would be activated during genuine unstable bodily states: The right parieto-insular vestibular cortex, inferior frontal junction, posterior insula and parabrachial nucleus. We argue that these right-lateralized cortical and brainstem regions mediate vestibular information processing for detection of vestibular anomalies, defensive motor responding in which the necessary motor responses are automatically prepared/simulated to protect one's own body, and sympathetic activity as a form of alarm response during whole body instability.
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影响因子：
1.7
作者：
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