Prior knowledge, older age, and higher allowance are risk factors for self-medication with antibiotics among university students in southern China.
Prior knowledge, older age, and higher allowance are risk factors for self-medication with antibiotics among university students in southern China.
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DOI：
10.1371/journal.pone.0041314
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发表时间：
2012
期刊：
影响因子：
3.7
通讯作者：
Ba-Thein W
中科院分区：
文献类型：
--
作者：
Pan H;Cui B;Zhang D;Farrar J;Law F;Ba-Thein W
许多国家都有大学生自行使用抗生素（SMA）的报道，但中国对此问题的研究还很少。本研究的目的是评估大学生的知识和行为以及有关 SMA 的危险因素。使用一种新颖的基于问卷的数据收集工具，对汕头大学（STU）的学生进行了匿名在线调查，汕头大学是一所位于中国广东东部的由 8 所学校/学院组成的大学。在 1,300 名受访者中（占合格参与者总数的 13.8%），47.8% 的人曾使用抗生素进行自我治疗。逻辑回归分析确定抗生素知识（PKA）、年龄较大和每月津贴较高是 SMA 的独立危险因素。 PKA 显着影响学生对抗生素及其用途和常见不良反应的了解（所有 p<0.05）。在自行用药的学生中，61.7%的人在上一年至少使用过两次抗生素。社区药房是自行处方抗生素的主要来源。据报道，SMA 的常见适应症是喉咙痛（59.7%）、发烧（38.2%）、咳嗽（37.4%）、流鼻涕（29.3%）和鼻塞（28.7%）。虽然 74.1% 的自我药疗事件是基于学生自己的经历，但只有 31.1% 的学生声称了解包装说明书。 63.8%和55.6%的学生在自我治疗过程中改变了抗生素和剂量。 82.6%的学生同时服用至少两种抗生素。大多数自行用药的学生未能完成抗生素课程。 16.3%的学生报告了不良反应。阿莫西林是最常用的自我药疗抗生素。 STU 学生中 SMA 患病率很高。研究人群中存在风险因素和风险相关行为/态度，需要有针对性的教育干预以及更严格的政府立法和药房抗生素使用和销售的监管。
Self-medication with antibiotics (SMA) has been reported among university students in many countries, but little research has been done on this issue in China. The objective of this study was to evaluate knowledge and behaviors of university students and risk factors concerning SMA. Using a novel questionnaire-based data collection instrument, an anonymous online survey was conducted with the students of Shantou University (STU), a university comprising 8 schools/colleges in eastern Guangdong, China. Of 1,300 respondents (13.8% of total eligible participants), 47.8% had self-treated with antibiotics. Logistic regression analysis identified prior knowledge of antibiotics (PKA), older age, and higher monthly allowance as independent risk factors for SMA. PKA significantly influenced students' knowledge about antibiotics, their uses, and common adverse reactions (all p<0.05). Among self-medicated students, 61.7% used antibiotics at least twice in the previous year. Community pharmacies were the major source of self-prescribed antibiotics. Reported common indications for SMA were sore throat (59.7%), fever (38.2%), cough (37.4%), runny nose (29.3%), and nasal congestion (28.7%). While 74.1% of self-medication episodes were based on students' own experiences, only 31.1% of students claimed to understand the package insert. Alteration of antibiotics and dosage during the course of self-treatment was made by 63.8% and 55.6% of students, respectively. At least two kinds of antibiotics were simultaneously taken by 82.6% of students. The majority of self-medicated students failed to complete the course of antibiotics. Adverse reactions were reported by 16.3% of students. Amoxicillin was the most common antibiotic used for self-medication. High prevalence of SMA was noted among STU students. Presence of risk factors and risk-associated behaviors/attitudes in the study population calls for focused educational intervention and stricter governmental legislation and regulation of antibiotic use and sale in pharmacies.
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影响因子：
2.9
作者：
Skliros E;Merkouris P;Papazafiropoulou A;Gikas A;Matzouranis G;Papafragos C;Tsakanikas I;Zarbala I;Vasibosis A;Stamataki P;Sotiropoulos A
通讯作者：
Sotiropoulos A
影响因子：
4.5
作者：
Sapkota AR;Coker ME;Rosenberg Goldstein RE;Atkinson NL;Sweet SJ;Sopeju PO;Ojo MT;Otivhia E;Ayepola OO;Olajuyigbe OO;Shireman L;Pottinger PS;Ojo KK
通讯作者：
Ojo KK
DOI：
10.2478/v10001-007-0038-9
发表时间：
2007-01-01
影响因子：
2
作者：
Al-Azzam, Sayer I.;Al-Husein, Belal A.;Al-Horani, Mohammad Ali S.
通讯作者：
Al-Horani, Mohammad Ali S.
DOI：
10.1046/j.1365-3156.1997.d01-213.x
发表时间：
1997-12-01
影响因子：
3.3
作者：
Duong, DV;Binns, CW;Van Le, T
通讯作者：
Van Le, T
影响因子：
11.8
作者：
McNulty, Cliodna A. M.;Boyle, Paul;Davey, Peter
通讯作者：
Davey, Peter