Pregnancy weight gain is not associated with maternal or mixed umbilical cord estrogen and androgen concentrations.
Pregnancy weight gain is not associated with maternal or mixed umbilical cord estrogen and androgen concentrations.
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DOI：
10.1007/s10552-008-9235-5
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发表时间：
2009-03
影响因子：
2.3
通讯作者：
Troisi, Rebecca
中科院分区：
文献类型：
--
作者：
Faupel-Badger, Jessica M.;Hoover, Robert N.;Potischman, Nancy;Roberts, James M.;Troisi, Rebecca
在75名健康的单胎妊娠妇女中探讨了母体体重增加与血清激素浓度的关系。雌激素，雌三醇，雌酮，雄烯二酮，睾酮，脱氢表雄酮（DHEA）和硫酸脱氢表雄酮的浓度进行了测量，在母体和混合脐带血清，以评估激素水平在母体和胎儿的循环在分娩。我们的数据显示母体或脐带类固醇激素浓度与妊娠体重增加无关。在怀孕期间增加类固醇激素，特别是雌激素的暴露，已经被假设在母亲和女性后代随后的乳腺癌风险中发挥作用。我们的研究结果与妊娠期体重增加的影响不一致，这是由这一途径介导的，反映在怀孕结束时的激素浓度。
The association of maternal weight gain with serum hormone concentrations was explored in 75 women who had healthy, singleton pregnancies. Estradiol, estriol, estrone, androstenedione, testosterone, dehydroepiandrosterone (DHEA) and DHEA sulfate concentrations were measured both in maternal and mixed umbilical cord serum to assess hormone levels in both the maternal and fetal circulation at delivery. Our data show no association of maternal or cord steroid hormone concentrations with pregnancy weight gain. Increased exposure to steroid hormones, especially estrogens, during pregnancy has been hypothesized to play a role in subsequent breast cancer risk for both mother and female offspring. Our results are not consistent with an effect of pregnancy weight gain being mediated by this pathway as reflected by hormone concentrations at the end of pregnancy.
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影响因子：
10.3
作者：
Ekbom, A;Hsieh, CC;Trichopoulos, D
通讯作者：
Trichopoulos, D
影响因子：
50.5
作者：
STOLL, BA
通讯作者：
STOLL, BA
影响因子：
7.7
作者：
Troisi, R;Potischman, N;Hoover, RN
通讯作者：
Hoover, RN
DOI：
10.1093/jnci/88.10.650
发表时间：
1996-05-15
期刊：
JOURNAL OF THE NATIONAL CANCER INSTITUTE
影响因子：
--
作者：
Ziegler, RG;Hoover, RN;Fraumeni, JF
通讯作者：
Fraumeni, JF
影响因子：
2.3
作者：
Troisi, R;Potischman, N;Hoover, RN
通讯作者：
Hoover, RN