Loihichelins A-F, a suite of amphiphilic siderophores produced by the marine bacterium Halomonas LOB-5.
Loihichelins A-F, a suite of amphiphilic siderophores produced by the marine bacterium Halomonas LOB-5.
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DOI：
10.1021/np800640h
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发表时间：
2009-05-22
影响因子：
5.1
通讯作者：
Butler, Alison
中科院分区：
文献类型：
--
作者：
Homann, Vanessa V.;Sandy, Moriah;Tincu, J. Andy;Templeton, Alexis S.;Tebo, Bradley M.;Butler, Alison
从海洋细菌盐单胞菌（Halomonassp. LOB-5）的培养物中分离出一组两亲性铁载体loihichelins A-F。这异养锰（II）氧化细菌最近分离的部分风化表面的海底玻璃枕玄武岩和相关的热液絮凝体的铁氧化物收集从南部裂谷带洛伊希海山以东的夏威夷。洛希克林含有亲水性头部基团，其由八肽组成，所述八肽由D-苏型-β-羟基天冬氨酸、D-丝氨酸、L-谷氨酰胺、L-丝氨酸、L-N（δ）-乙酰基-N（δ）-羟基鸟氨酸、脱氢氨基-2-丁酸、D-丝氨酸和环状N（δ）-羟基-D-鸟氨酸组成，并附加有从癸酸至十四烷酸的一系列脂肪酸之一。通过氨基酸和脂肪酸分析、串联质谱和NMR光谱的组合确定了loihichelin C的结构。从氨基酸和脂肪酸分析以及串联质谱推断其他loihichelin的结构。这些铁载体在螯合玄武岩风化过程中释放的Fe（III）的作用，以及它们在促进Mn（II）和Fe（II）氧化中的潜在作用，是相当感兴趣的。
A suite of amphiphilic siderophores, loihichelins A-F, were isolated from cultures of the marine bacterium Halomonas sp. LOB-5. This heterotrophic Mn(II)-oxidizing bacterium was recently isolated from the partially weathered surfaces of submarine glassy pillow basalts and associated hydrothermal flocs of iron oxides collected from the southern rift zone of Loihi Seamount east of Hawai’i. The loihichelins contain a hydrophilic head group consisting of an octapeptide comprised of D-threo-β-hydroxyaspartic acid, D-serine, L-glutamine, L-serine, L-N(δ)-acetyl-N(δ)-hydroxy ornithine, dehydroamino-2-butyric acid, D-serine and cyclic N(δ)-hydroxy-D-ornithine, appended by one of a series of fatty acids ranging from decanoic acid to tetradecanoic acid. The structure of loihichelin C was determined by a combination of amino acid and fatty acid analyses, tandem mass spectrometry and NMR spectroscopy. The structures of the other loihichelins were inferred from the amino acid and fatty acid analyses, and tandem mass spectrometry. The role of these siderophores in sequestering Fe(III) released during basaltic rock weathering, as well as their potential role in the promotion of Mn(II) and Fe(II) oxidation, is of considerable interest.
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影响因子：
3.2
作者：
HUIJBERTS, GNM;DERIJK, TC;EGGINK, G
通讯作者：
EGGINK, G
影响因子：
3.5
作者：
Butler, A
通讯作者：
Butler, A
影响因子：
64.8
作者：
Barbeau, K;Rue, EL;Butler, A
通讯作者：
Butler, A
影响因子：
4.1
作者：
SNOW, GA
通讯作者：
SNOW, GA
DOI：
10.1073/pnas.0600830103
发表时间：
2006-04-25
影响因子：
11.1
作者：
Staudigel, H;Hart, SR;Young, CM
通讯作者：
Young, CM